BRENDA - Enzyme Database
show all sequences of 1.5.1.11

Octopine dehydrogenase of a Vinca rosea crown gall-tumor

Birnberg, P.R.; Rao, S.S.; Lippincott, J.A.; Phytochemistry 22, 1345-1355 (1983)
No PubMed abstract available

Data extracted from this reference:

General Stability
General Stability
Organism
the apoenzyme is protected against inactivation by NADP+
Catharanthus roseus
Inhibitors
Inhibitors
Commentary
Organism
Structure
Methyl octopine
-
Catharanthus roseus
NADH
substrate inhibition
Catharanthus roseus
NADP+
-
Catharanthus roseus
NADPH
substrate inhibition
Catharanthus roseus
pyruvate
substrate inhibition
Catharanthus roseus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
dependence of the Km-values for Arg and pyruvate on the concentration of the other substrates
Catharanthus roseus
0.001
0.01
NADPH
-
Catharanthus roseus
0.015
-
NADP+
-
Catharanthus roseus
0.7
-
L-Orn
with pyruvate and NADPH as cosubstrates
Catharanthus roseus
1
-
oxaloacetate
L-Lys, with pyruvate and NADPH as cosubstrates
Catharanthus roseus
2.7
-
L-Gln
with pyruvate and NADPH as cosubstrates
Catharanthus roseus
3.9
-
L-canavanine
with pyruvate and NADPH as cosubstrates
Catharanthus roseus
5.1
-
L-Arg
with pyruvate and NADPH as cosubstrate
Catharanthus roseus
5.4
-
L-Cys
with pyruvate and NADPH as cosubstrate
Catharanthus roseus
22
-
L-citrulline
L-Met, with pyruvate and NADPH as cosubstrate; with pyruvate and NADPH as cosubstrates
Catharanthus roseus
23
-
L-His
with pyruvate and NADPH as cosubstrate
Catharanthus roseus
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Catharanthus roseus
the enzyme may synthesize lysopine, octopinic acid, and the corresponding Nalpha-derivatives of glutamine
?
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Catharanthus roseus
-
-
-
Purification (Commentary)
Commentary
Organism
crown-gall tumor-tissue induced by Agrobacterium tumefaciens
Catharanthus roseus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
crown gall
cell lines of
Catharanthus roseus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Canavanine + pyruvate + NADPH
at 56% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-canavanine + NADP+ + H2O
-
-
-
-
Homoarginine + pyruvate + NADPH
at 62% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-homoarginine + NADP+ + H2O
-
-
-
-
L-Arg + 2-oxobutanoate + NADPH
at 21% of the activity with pyruvate
13323
Catharanthus roseus
N2-(D-2-Carboxypropyl)-L-Arg + NADP+ + H2O
-
-
-
-
L-Arg + glyoxylate + NADPH
at 5% of the activity with pyruvate
13323
Catharanthus roseus
?
-
-
-
-
L-Arg + oxaloacetate + NADH
-
13323
Catharanthus roseus
?
-
-
-
-
L-Arg + pyruvate + NADH
-
13323
Catharanthus roseus
N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O
-
13323
Catharanthus roseus
-
L-Arg + pyruvate + NADPH
-
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Arg + NADP+ + H2O
-
-
-
-
L-Citrulline + pyruvate + NADPH
-
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-citrulline + NADP+ + H2O
-
-
-
-
L-Cys + pyruvate + NADPH
at 27% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Cys + NADP+ + H2O
-
-
-
-
L-Gln + pyruvate + NADPH
at 18% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Gln + NADP+ + H2O
-
-
-
-
L-His + pyruvate + NADPH
at 78% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-His + NADP+ + H2O
-
-
-
-
L-Lys + pyruvate + NADPH
at 31% of the activity with L-Arg
13323
Catharanthus roseus
Lysopine + NADP+ + H2O
-
-
-
-
L-Met + pyruvate + NADPH
at 67% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Met + NADP+ + H2O
-
-
-
-
L-serine + pyruvate + NADPH
at 25% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-carboxyethyl)-L-Ser + NADP+ + H2O
-
-
-
-
additional information
the enzyme may synthesize lysopine, octopinic acid, and the corresponding Nalpha-derivatives of glutamine
13323
Catharanthus roseus
?
-
-
-
-
Orn + pyruvate + NADPH
at 30% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Orn + NADP+ + H2O
-
-
-
-
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5.2
-
with Lys or Orn as substrate
Catharanthus roseus
6
6.6
with Arg or His as substrate
Catharanthus roseus
9.2
-
octopine oxidation
Catharanthus roseus
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
6.5
8.5
4°C, stable. Loses most of its activity after 24 h at lower or higher pH-values
Catharanthus roseus
Cofactor
Cofactor
Commentary
Organism
Structure
NADH
-
Catharanthus roseus
NADPH
-
Catharanthus roseus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADH
-
Catharanthus roseus
NADPH
-
Catharanthus roseus
General Stability (protein specific)
General Stability
Organism
the apoenzyme is protected against inactivation by NADP+
Catharanthus roseus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
Methyl octopine
-
Catharanthus roseus
NADH
substrate inhibition
Catharanthus roseus
NADP+
-
Catharanthus roseus
NADPH
substrate inhibition
Catharanthus roseus
pyruvate
substrate inhibition
Catharanthus roseus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
dependence of the Km-values for Arg and pyruvate on the concentration of the other substrates
Catharanthus roseus
0.001
0.01
NADPH
-
Catharanthus roseus
0.015
-
NADP+
-
Catharanthus roseus
0.7
-
L-Orn
with pyruvate and NADPH as cosubstrates
Catharanthus roseus
1
-
oxaloacetate
L-Lys, with pyruvate and NADPH as cosubstrates
Catharanthus roseus
2.7
-
L-Gln
with pyruvate and NADPH as cosubstrates
Catharanthus roseus
3.9
-
L-canavanine
with pyruvate and NADPH as cosubstrates
Catharanthus roseus
5.1
-
L-Arg
with pyruvate and NADPH as cosubstrate
Catharanthus roseus
5.4
-
L-Cys
with pyruvate and NADPH as cosubstrate
Catharanthus roseus
22
-
L-citrulline
L-Met, with pyruvate and NADPH as cosubstrate; with pyruvate and NADPH as cosubstrates
Catharanthus roseus
23
-
L-His
with pyruvate and NADPH as cosubstrate
Catharanthus roseus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Catharanthus roseus
the enzyme may synthesize lysopine, octopinic acid, and the corresponding Nalpha-derivatives of glutamine
?
-
-
-
Purification (Commentary) (protein specific)
Commentary
Organism
crown-gall tumor-tissue induced by Agrobacterium tumefaciens
Catharanthus roseus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
crown gall
cell lines of
Catharanthus roseus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Canavanine + pyruvate + NADPH
at 56% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-canavanine + NADP+ + H2O
-
-
-
-
Homoarginine + pyruvate + NADPH
at 62% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-homoarginine + NADP+ + H2O
-
-
-
-
L-Arg + 2-oxobutanoate + NADPH
at 21% of the activity with pyruvate
13323
Catharanthus roseus
N2-(D-2-Carboxypropyl)-L-Arg + NADP+ + H2O
-
-
-
-
L-Arg + glyoxylate + NADPH
at 5% of the activity with pyruvate
13323
Catharanthus roseus
?
-
-
-
-
L-Arg + oxaloacetate + NADH
-
13323
Catharanthus roseus
?
-
-
-
-
L-Arg + pyruvate + NADH
-
13323
Catharanthus roseus
N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O
-
13323
Catharanthus roseus
-
L-Arg + pyruvate + NADPH
-
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Arg + NADP+ + H2O
-
-
-
-
L-Citrulline + pyruvate + NADPH
-
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-citrulline + NADP+ + H2O
-
-
-
-
L-Cys + pyruvate + NADPH
at 27% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Cys + NADP+ + H2O
-
-
-
-
L-Gln + pyruvate + NADPH
at 18% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Gln + NADP+ + H2O
-
-
-
-
L-His + pyruvate + NADPH
at 78% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-His + NADP+ + H2O
-
-
-
-
L-Lys + pyruvate + NADPH
at 31% of the activity with L-Arg
13323
Catharanthus roseus
Lysopine + NADP+ + H2O
-
-
-
-
L-Met + pyruvate + NADPH
at 67% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Met + NADP+ + H2O
-
-
-
-
L-serine + pyruvate + NADPH
at 25% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-carboxyethyl)-L-Ser + NADP+ + H2O
-
-
-
-
additional information
the enzyme may synthesize lysopine, octopinic acid, and the corresponding Nalpha-derivatives of glutamine
13323
Catharanthus roseus
?
-
-
-
-
Orn + pyruvate + NADPH
at 30% of the activity with L-Arg
13323
Catharanthus roseus
N2-(D-1-Carboxyethyl)-L-Orn + NADP+ + H2O
-
-
-
-
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5.2
-
with Lys or Orn as substrate
Catharanthus roseus
6
6.6
with Arg or His as substrate
Catharanthus roseus
9.2
-
octopine oxidation
Catharanthus roseus
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
6.5
8.5
4°C, stable. Loses most of its activity after 24 h at lower or higher pH-values
Catharanthus roseus
Other publictions for EC 1.5.1.11
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743404
Murphy
Changes to coral health and m ...
Montipora capitata
PeerJ
4
e1956
2016
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-
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1
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2
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1
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1
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1
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1
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1
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1
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1
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1
1
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-
743588
Watanabe
Characterization of flavin-co ...
Agrobacterium tumefaciens
PLoS ONE
10
e0138434
2015
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1
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2
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1
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1
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4
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1
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1
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1
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1
1
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1
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4
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1
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1
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741868
Lagana
-
Anaerobiosis and metabolic pl ...
Pinna nobilis
Biochem. Syst. Ecol.
56
138-143
2014
1
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1
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1
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5
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5
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1
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1
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2
2
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725623
van Os
Control of D-octopine formatio ...
Pecten maximus
J. Exp. Biol.
215
1515-1522
2012
-
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1
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1
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4
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1
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3
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1
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1
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1
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3
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1
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724787
Vazquez-Dorado
Identification of octopine deh ...
Mytilus galloprovincialis
Comp. Biochem. Physiol. B
160
94-103
2011
-
-
1
-
-
-
-
7
-
-
2
-
-
8
-
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1
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1
7
-
6
1
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1
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1
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1
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1
1
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7
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2
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1
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1
7
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6
1
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1
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1
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713370
Smits
Insights into the mechanism of ...
Pecten maximus
PLoS ONE
5
e12312
2010
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1
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3
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1
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3
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688422
Smits
A structural basis for substra ...
Pecten maximus
J. Mol. Biol.
381
200-211
2008
-
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1
1
2
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11
-
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3
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1
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3
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8
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11
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1
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1
1
1
2
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11
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1
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3
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8
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11
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701492
Smits
Coenzyme- and His-tag-induced ...
Pecten maximus
Acta Crystallogr. Sect. F
64
836-839
2008
-
1
1
1
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1
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686683
Mueller
Putative reaction mechanism of ...
Pecten maximus
FEBS J.
274
6329-6339
2007
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1
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5
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3
18
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2
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4
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1
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3
2
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1
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18
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1
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1
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1
1
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5
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3
-
18
-
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2
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1
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3
2
-
1
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-
18
-
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1
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13288
Mulcahy
Biospecific affinity chromatog ...
Chlamys opercularis, Loligo vulgaris, Mytilus edulis, Pecten maximus, Phorcus lineatus
Protein Expr. Purif.
9
109-114
1997
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13
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5
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4
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5
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5
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5
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5
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5
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13294
Coughlan
The lysopine and octopine dehy ...
Mytilus edulis
Biochem. Soc. Trans.
24
128S
1996
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3
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1
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1
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4
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13290
Carvajal
-
Lactate dehydrogenase, alanopi ...
Concholepas concholepas
Comp. Biochem. Physiol. B
108
543-550
1994
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2
5
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1
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1
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1
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1
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1
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1
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5
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1
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-
-
-
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
13289
Sheikh
Involvement of different cyste ...
Pecten jacobaeus
Biochem. Mol. Biol. Int.
29
719-727
1993
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13291
Hammen
-
Opine oxidoreductases in marin ...
Cerebratulus sp., Lineus sp., no activity in Amphitrite sp., no activity in Chaetopterus variopedatus, no activity in Clymenella torquata, no activity in Glycera sp., no activity in Hydroides sp., no activity in Lepidonotus sp., no activity in Nereis sp., no activity in Phascolopsis sp., no activity in Phascolosoma sp., no activity in Themiste sp., no activity in Urechis sp., Priapulus sp.
Comp. Biochem. Physiol. B
106
989-992
1993
-
-
-
-
-
-
-
-
-
-
-
-
-
14
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13292
Sato
-
Distribution of opine dehydrog ...
Anthopleura nigrescens, Azumapecten farreri nipponensis, Buccinum isaotakii, Fusitriton oregonensis, Haliotis discus hannai, Heterololigo bleekeri, Littorina brevicula, Meretrix lusoria, Mizuhopecten yessoensis, Mytilus edulis, Neptunea arthritica, Octopus membranaceus, Octopus vulgaris, Perinereis nuntia, Pseudocardium sachalinense, Reishia clavigera, Ruditapes philippinarum, Scapharca broughtonii, Todarodes pacificus, Tugali gigas
Comp. Biochem. Physiol. B
106
955-960
1993
-
-
-
-
-
-
-
-
-
-
-
-
-
20
-
-
-
-
-
-
-
-
20
-
-
-
-
-
-
-
-
20
-
-
-
-
-
-
20
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
20
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13315
Seikh
Chemical medification of octop ...
Pecten maximus
Biochim. Biophys. Acta
1202
251-257
1993
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13293
Santulli
-
Two tissue-specific loci for o ...
Ruditapes decussatus
Comp. Biochem. Physiol. B
102
409-411
1992
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
5
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13300
Hammen
-
Opine oxidoreductases in brach ...
Anadara ovalis, Dentalium pilsbryi, Haliotis rufescens, no activity in Bugula neritina, no activity in Chaetopleura apiculata, no activity in Crepidula fornicata, no activity in Diodora cayenensis, no activity in Glottidia pyramidata, no activity in Laqueus californianus, no activity in Littorina littorea, no activity in Lyonsia hyalina, no activity in Membranipora tenuis, no activity in Mopalia muscosa, no activity in Mya arenaria, no activity in Phoronis architecta, no activity in Phoronis vancouverensis, no activity in Schizoporella floridana, no activity in Tectura testudinalis, no activity in Tegula funebralis, no activity in Terebratalia transversa, no activity in Turbo castanea, no activity in Urosalpinx cinerea, Nucella lapillus, Nucula proxima, Solemya velum, Spisula solidissima
Biochem. Syst. Ecol.
19
263-269
1991
-
-
-
-
-
-
-
-
-
-
-
-
-
26
-
-
-
-
-
2
-
-
7
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13296
Carvajal
-
Kinetic mechanism of octopine ...
Concholepas concholepas
Biochim. Biophys. Acta
953
14-19
1988
-
-
-
-
-
-
4
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13297
Teschner
-
Intermediates on the folding p ...
Pecten jacobaeus
Biochemistry
26
2791-2796
1987
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13295
Gäde
-
Purification and characterisat ...
Cerebratulus lacteus, Pecten jacobaeus
Mar. Biol.
79
39-45
1984
-
-
-
-
-
-
1
5
-
-
2
-
-
2
-
-
1
-
-
1
1
-
12
1
-
-
-
-
1
1
-
2
-
-
-
-
-
-
2
-
-
-
-
1
-
5
-
-
2
-
-
-
-
1
-
1
1
-
12
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
13298
Schrimsher
Octopine dehydrogenase from Pe ...
Pecten maximus
Biochemistry
23
1348-1353
1984
-
-
-
-
-
-
4
-
-
-
-
-
-
2
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13299
Zettlmeissl
Isolation, physicochemical pro ...
Pecten jacobaeus
Eur. J. Biochem.
143
401-407
1984
-
-
-
-
-
-
-
5
-
-
-
-
-
2
-
-
1
-
1
2
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
5
-
-
-
-
-
-
-
1
1
2
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
13323
Birnberg
-
Octopine dehydrogenase of a Vi ...
Catharanthus roseus
Phytochemistry
22
1345-1355
1983
-
-
-
-
-
1
5
11
-
-
-
1
-
1
-
-
1
-
-
1
-
-
16
-
-
-
-
-
3
-
1
2
-
-
-
-
-
-
2
-
-
1
-
5
-
11
-
-
-
1
-
-
-
1
-
1
-
-
16
-
-
-
-
-
3
-
1
-
-
-
-
-
-
-
13301
Storey
-
Substrate specificities of oct ...
Arctica islandica, Calliactis parasitica, Cerastoderma edule, Glycymeris glycymeris, Mytilus edulis, Pecten maximus, Sepia officinalis
Comp. Biochem. Physiol. B
73
521-528
1982
-
-
-
-
-
-
-
59
-
-
-
5
-
7
-
-
-
-
-
11
-
-
50
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
7
-
-
-
-
-
-
59
-
-
-
5
-
-
-
-
-
11
-
-
50
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13321
Schrimsher
Octopine dehydrogenase from cr ...
Nicotiana tabacum, Pecten maximus
J. Biol. Chem.
257
8953-8956
1982
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
2
-
3
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13322
Murai
Octopine synthase mRNA isolate ...
Helianthus annuus
Proc. Natl. Acad. Sci. USA
79
86-90
1982
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
5
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13303
Monneuse-Doublet
-
A proposed kinetic mechanism f ...
Pecten maximus
Biochem. Soc. Trans.
9
300-302
1981
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13304
Olomucki
Structure and function of octo ...
Pecten maximus
Biochem. Soc. Trans.
9
278-279
1981
-
-
-
1
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13305
Barrett
-
Octopine dehydrogenase in gast ...
Buccinum undatum, Gibbula umbilicalis, Nucella lapillus, Patella aspera, Patella vulgata, Phorcus lineatus
Experientia
37
958-959
1981
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13317
Walsh
-
Purification and characterizat ...
Metridium senile
J. Comp. Physiol.
143
213-222
1981
-
-
-
-
-
-
4
1
-
-
2
-
-
1
-
-
1
-
-
-
1
-
7
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
4
-
1
-
-
2
-
-
-
-
1
-
-
1
-
7
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13302
Gäde
-
A comparative study of octopin ...
Buccinum undatum, Cardium tuberculatum, Loligo vulgaris, Mytilus edulis, Pecten jacobaeus
Comp. Biochem. Physiol. B
67
575-582
1980
-
-
-
-
-
-
2
27
-
-
-
2
-
5
-
-
-
-
-
18
-
-
8
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
5
-
-
-
-
2
-
27
-
-
-
2
-
-
-
-
-
18
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13314
Monneuse-Doublet
Isolation and characterization ...
Pecten maximus
Eur. J. Biochem.
108
261-269
1980
-
-
-
-
-
-
-
1
-
-
1
-
-
3
-
-
1
-
-
3
1
-
1
1
-
-
1
-
2
-
1
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
-
1
-
3
1
-
1
1
-
-
1
-
2
-
1
-
-
-
-
-
-
-
13319
Hack
Purification and characterizat ...
Helianthus annuus
Plant Physiol.
65
949-955
1980
-
-
-
-
-
-
2
3
-
-
2
-
-
4
-
-
1
1
-
1
1
1
6
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
2
-
3
-
-
2
-
-
-
-
1
-
1
1
1
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13306
Gäde
-
A rapid method for the purific ...
Pecten maximus
Experientia
35
304-305
1979
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13312
Storey
Kinetic characterization of ti ...
Sepia officinalis
Eur. J. Biochem.
93
545-552
1979
-
-
-
-
-
-
4
9
-
-
-
2
-
2
-
-
-
-
-
4
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
4
-
9
-
-
-
2
-
-
-
-
-
4
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13320
Birnberg
-
Two octopine dehydrogenases in ...
Catharanthus roseus, Nicotiana tabacum, Phaseolus vulgaris
Phytochemistry
16
647-650
1977
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
3
-
-
4
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13318
Gäde
Octopine dehydrogenase in the ...
Cerastoderma edule
Biochem. Soc. Trans.
4
433-436
1976
-
-
-
-
-
-
-
2
-
-
1
-
-
2
-
-
1
-
-
-
-
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
1
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
13309
Huc
Modification of the essential ...
Pecten maximus
FEBS Lett.
60
414-418
1975
-
-
-
-
-
-
1
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13310
Luisi
Temperature-determined enzymat ...
Pecten maximus
Eur. J. Biochem.
50
511-516
1975
-
-
-
-
-
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
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1
-
-
-
-
-
-
-
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-
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-
13311
Doublet
Investigations on the kinetic ...
Pecten maximus
Eur. J. Biochem.
59
175-183
1975
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-
-
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-
-
3
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13308
Thome-Beau
Presence of a single essential ...
Pecten maximus
Eur. J. Biochem.
39
557-562
1973
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-
-
-
-
-
-
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-
-
-
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-
1
1
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-
-
-
-
-
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1
-
-
-
-
-
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1
-
-
-
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1
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-
-
-
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-
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1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
13316
Olomucki
Octopine dehydrogenase. Eviden ...
Pecten maximus
Eur. J. Biochem.
28
261-268
1972
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-
-
-
-
-
-
-
-
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3
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1
-
-
-
-
-
-
-
-
1
1
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-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
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3
-
-
-
-
-
-
-
-
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1
1
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-
13307
Huc
Essential histidyl residues of ...
Pecten maximus
Eur. J. Biochem.
21
161-169
1971
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-
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1
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1
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1
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1
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1
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1
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-
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1
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13313
Van Thoai
Octopine deshydrogenase. Purif ...
Pecten maximus
Biochim. Biophys. Acta
191
46-57
1969
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7
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1
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1
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1
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1
-
-
-
-
-
-
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1
-
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-
-
-
-
1
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-
-
7
-
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-
-
-
-
-
-
1
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-
1
-
1
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-