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Literature summary for 1.5.1.10 extracted from

  • Andi, B.; Cook, P.F.; West, A.H.
    Crystal structure of the his-tagged saccharopine reductase from Saccharomyces cerevisiae at 1.7-A resolution (2006), Cell Biochem. Biophys., 46, 17-26.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
apo form of enzyme. Protein consists of domain I, a variant of the Rossman fold and binding to NADPH, domain II with an alpha/beta structure and binding saccharopine, and domain III with all-helical fold involved in closing the active site of the enzyme once substrates are bound Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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