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Literature summary for 1.4.99.2 extracted from

  • Mostafavi, M.; Lewis, J.; Saini, T.; Bustamante, J.; Gao, I.; Tran, T.; King, S.; Huang, Z.; Chen, J.
    Analysis of a taurine-dependent promoter in Sinorhizobium meliloti that offers tight modulation of gene expression (2014), BMC Microbiol., 14, 295 .
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
gene tauY (SMb21529) encodes the large subunit of the putative taurine dehydrogenas, expression analysis in wild-type and mutant strainse Sinorhizobium meliloti

Protein Variants

Protein Variants Comment Organism
additional information in-frame deletion of gene tauY. Individual deletion mutants of tauR, tauC, and tauY, show growth defects. Growth is restored when each mutant is complemented with the appropriate gene on a plasmid, suggesting that the individual deletions do not deter expression of downstream genes, they are not polar mutations. Induced or uninduced DELTAtauY mutant displays the highest levels of reporter expression compared to other strains grown under similar conditions. Increased accumulation of taurine, and thus enhanced expression, occurs in the DELTAtauY mutant due to its inability to degrade the sulfonate compound Sinorhizobium meliloti

Organism

Organism UniProt Comment Textmining
Sinorhizobium meliloti
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-
-

Synonyms

Synonyms Comment Organism
taurine dehydrogenase
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 Sinorhizobium meliloti
TauY
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 Sinorhizobium meliloti

General Information

General Information Comment Organism
malfunction individual deletion mutants of tauR, tauC, and tauY, show growth defects. Growth is restored when each mutant is complemented with the appropriate gene on a plasmid, suggesting that the individual deletions do not deter expression of downstream genes, they are not polar mutations. Induced or uninduced DELTAtauY mutant displays the highest levels of reporter expression compared to other strains grown under similar conditions. Increased accumulation of taurine, and thus enhanced expression, occurs in the DELTAtauY mutant due to its inability to degrade the sulfonate compound Sinorhizobium meliloti
physiological function the genes of the tau region, tauR, tauC, and tauY, are each required for taurine dissimilation in Sinorhizobium meliloti. Enzyme TauY is involved in the degradation of taurine, most likely by forming part of the taurine dehydrogenase Sinorhizobium meliloti