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BRENDA support

Literature summary for 1.4.9.2 extracted from

  • Massgrau, L.; Roujeinikova, A.; Johannissen, L.O.; Hothi, P.; Basran, J.; Ranaghan, K.E.; Mulholland, A.J.; Sutcliffe, M.J.; Scrutton, N.S.; Leys, D.
    Atomic description of an enzyme reaction dominated by proton tunneling. (2006), Science, 312, 237-241.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Alcaligenes faecalis
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Reaction

Reaction Comment Organism Reaction ID
ArCH2NH2 + H2O + 2 azurin = ArCHO + NH3 + 2 reduced azurin proton transfer occurs predominantly to oxygen O2 of D128 in beta subunit in a reaction dominated by tunneling over 0.6 Angstroms. Tunneling is promoted by a short-range motion modulating proton-acceptor distance and no long-range coupled motion is required Alcaligenes faecalis