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Literature summary for 1.4.3.5 extracted from

  • Ankisettypalli, K.; Cheng, J.J.; Baker, E.N.; Bashiri, G.
    PdxH proteins of Mycobacteria are typical members of the classical pyridoxine/pyridoxamine 5-phosphate oxidase family (2016), FEBS Lett., 590, 453-460 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyridoxamine 5'-phosphate + H2O + O2 Mycobacterium tuberculosis
-
pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxamine 5'-phosphate + H2O + O2 Mycobacterium marinum
-
pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxamine 5'-phosphate + H2O + O2 Mycolicibacterium smegmatis
-
pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxamine 5'-phosphate + H2O + O2 Mycolicibacterium smegmatis mc(2)155 / ATCC 700084
-
pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxamine 5'-phosphate + H2O + O2 Mycobacterium tuberculosis H37Rv
-
pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxine 5'-phosphate + O2 Mycobacterium tuberculosis
-
pyridoxal 5'-phosphate + H2O2
-
?
pyridoxine 5'-phosphate + O2 Mycobacterium marinum
-
pyridoxal 5'-phosphate + H2O2
-
?
pyridoxine 5'-phosphate + O2 Mycolicibacterium smegmatis
-
pyridoxal 5'-phosphate + H2O2
-
?
pyridoxine 5'-phosphate + O2 Mycolicibacterium smegmatis mc(2)155 / ATCC 700084
-
pyridoxal 5'-phosphate + H2O2
-
?
pyridoxine 5'-phosphate + O2 Mycobacterium tuberculosis H37Rv
-
pyridoxal 5'-phosphate + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Mycobacterium marinum B2HF83
-
-
Mycobacterium tuberculosis
-
-
-
Mycobacterium tuberculosis H37Rv
-
-
-
Mycolicibacterium smegmatis A0R420
-
-
Mycolicibacterium smegmatis mc(2)155 / ATCC 700084 A0R420
-
-

Purification (Commentary)

Purification (Comment) Organism
HisTrap nickel-affinity column chromatography and Superdex 200 gel filtration Mycobacterium tuberculosis
HisTrap nickel-affinity column chromatography and Superdex 200 gel filtration Mycobacterium marinum
HisTrap nickel-affinity column chromatography and Superdex 200 gel filtration Mycolicibacterium smegmatis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyridoxamine 5'-phosphate + H2O + O2
-
Mycobacterium tuberculosis pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxamine 5'-phosphate + H2O + O2
-
Mycobacterium marinum pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxamine 5'-phosphate + H2O + O2
-
Mycolicibacterium smegmatis pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxamine 5'-phosphate + H2O + O2
-
Mycolicibacterium smegmatis mc(2)155 / ATCC 700084 pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxamine 5'-phosphate + H2O + O2
-
Mycobacterium tuberculosis H37Rv pyridoxal 5'-phosphate + NH3 + H2O2
-
?
pyridoxine 5'-phosphate + O2
-
Mycobacterium tuberculosis pyridoxal 5'-phosphate + H2O2
-
?
pyridoxine 5'-phosphate + O2
-
Mycobacterium marinum pyridoxal 5'-phosphate + H2O2
-
?
pyridoxine 5'-phosphate + O2
-
Mycolicibacterium smegmatis pyridoxal 5'-phosphate + H2O2
-
?
pyridoxine 5'-phosphate + O2
-
Mycolicibacterium smegmatis mc(2)155 / ATCC 700084 pyridoxal 5'-phosphate + H2O2
-
?
pyridoxine 5'-phosphate + O2
-
Mycobacterium tuberculosis H37Rv pyridoxal 5'-phosphate + H2O2
-
?

Synonyms

Synonyms Comment Organism
PdxH
-
Mycobacterium tuberculosis
PdxH
-
Mycobacterium marinum
PdxH
-
Mycolicibacterium smegmatis
PNPOx
-
Mycobacterium tuberculosis
PNPOx
-
Mycobacterium marinum
PNPOx
-
Mycolicibacterium smegmatis
pyridoxine/pyridoxamine 5'-phosphate oxidase
-
Mycobacterium tuberculosis
pyridoxine/pyridoxamine 5'-phosphate oxidase
-
Mycobacterium marinum
pyridoxine/pyridoxamine 5'-phosphate oxidase
-
Mycolicibacterium smegmatis