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Literature summary for 1.4.3.4 extracted from

  • Dreiseitel, A.; Korte, G.; Schreier, P.; Oehme, A.; Locher, S.; Domani, M.; Hajak, G.; Sand, P.G.
    Berry anthocyanins and their aglycons inhibit monoamine oxidases A and B (2009), Pharmacol. Res., 59, 306-311.
    View publication on PubMed
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
3-(4-hydroxyphenyl)propionic acid
-
 Homo sapiens
3-hydroxyphenylacetic acid
-
 Homo sapiens
4-hydroxyphenylacetic acid
-
 Homo sapiens
cyanidin competitive interaction of cyanidin with MAO A plus a mixed competitive and non-competitive mode of interaction of cyanidin with MAO B Homo sapiens
cyanidin-3,5-diglucoside
-
 Homo sapiens
cyanidin-3-O-beta-D-galactoside
-
 Homo sapiens
cyanidin-3-O-beta-D-glucoside mixed competitive and non-competitive mode of interaction with both enzyme isozymes Homo sapiens
cyanidin-3-O-beta-D-rutinoside
-
 Homo sapiens
delphinidin
-
 Homo sapiens
delphinidin-3-O-beta-D-glucoside
-
 Homo sapiens
malvidin
-
 Homo sapiens
malvidin 3-O,5-O-di-beta-D-glucoside
-
 Homo sapiens
malvidin-3-O-beta-D-galactoside
-
 Homo sapiens
malvidin-3-O-beta-D-glucoside
-
 Homo sapiens
additional information 25 anthocyanidins, anthocyanidin-3-glycosides, anthocyanidin-3,5-diglucosides, proanthocyanidins, and phenolic metabolites are examined as MAO inhibitors, overview Homo sapiens
pelargonidin
-
 Homo sapiens
pelargonidin 3-O,5-O-di-beta-D-glucoside
-
 Homo sapiens
peonidin
-
 Homo sapiens
peonidin-3-O-beta-D-glucoside
-
 Homo sapiens
petunidin
-
 Homo sapiens
syringic acid
-
 Homo sapiens
vanillic acid
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
commercial preparation recombinant isozymes MAO A and MAO B, expressed in baculovirus-infected insect cells BTI-TN-5B1-4 Homo sapiens
-

Synonyms

Synonyms Comment Organism
MAO-A
-
 Homo sapiens
MAO-B
-
 Homo sapiens
monoamine oxidase A
-
 Homo sapiens
monoamine oxidase B
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0204
-
 cyanidin pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens
0.0317
-
 cyanidin pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens
0.0474
-
 cyanidin-3-O-beta-D-glucoside pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens
0.0586
-
 cyanidin pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens
0.0611
-
 cyanidin-3-O-beta-D-glucoside pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0187
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens malvidin
0.0221
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens malvidin
0.0221
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens peonidin
0.0268
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens pelargonidin
0.0294
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens delphinidin-3-O-beta-D-glucoside
0.0295
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin
0.0305
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens peonidin
0.0314
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens delphinidin-3-O-beta-D-glucoside
0.0315
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens petunidin
0.0332
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin-3-O-beta-D-rutinoside
0.0341
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens malvidin-3-O-beta-D-galactoside
0.0343
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin-3-O-beta-D-glucoside
0.0348
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens delphinidin
0.0351
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens cyanidin-3-O-beta-D-rutinoside
0.0359
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin-3-O-beta-D-galactoside
0.0368
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens malvidin-3-O-beta-D-glucoside
0.038
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens delphinidin
0.0381
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens peonidin-3-O-beta-D-glucoside
0.0393
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens malvidin-3-O-beta-D-galactoside
0.0407
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens peonidin-3-O-beta-D-glucoside
0.0426
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens pelargonidin
0.0432
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens petunidin
0.0464
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens cyanidin-3-O-beta-D-galactoside
0.0478
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens malvidin-3-O-beta-D-glucoside
0.0616
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens malvidin 3-O,5-O-di-beta-D-glucoside
0.0733
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens malvidin 3-O,5-O-di-beta-D-glucoside
0.113
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin-3,5-diglucoside
0.1173
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens pelargonidin 3-O,5-O-di-beta-D-glucoside
0.152
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens cyanidin-3,5-diglucoside
0.242
-
 pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens pelargonidin 3-O,5-O-di-beta-D-glucoside
3.89
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens vanillic acid
4.16
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens syringic acid
11.52
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens 3-(4-hydroxyphenyl)propionic acid
17.75
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens 3-hydroxyphenylacetic acid
20.28
-
 pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens 4-hydroxyphenylacetic acid