Any feedback?
Literature summary for 1.4.3.4 extracted from
- Monoamine oxidase inhibitory activities of the scorpion Mesobuthus gibbosus (Buthidae) venom peptides (2005), Toxicon, 45, 43-52.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Clorgyline | - |
Rattus norvegicus |  |
| Mesobuthus gibbosus venom peptide | with specific MAO-A inhibitory activity, reversible, non-competitive, may be responsible for the anxiogenic effects of the scorpion venom on animals and humans | Rattus norvegicus | |
| additional information | no inhibition by Mesobuthus gibbosus venom peptide | Homo sapiens | |
| additional information | no inhibition by Mesobuthus gibbosus venom peptide | Rattus norvegicus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.02031 | - |
p-tyramine | - |
Rattus norvegicus | |
| 0.061 | - |
p-tyramine | - |
Rattus norvegicus | |
| 0.19 | - |
p-tyramine | - |
Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Homo sapiens | 5739 | - |
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood platelet | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| p-tyramine + H2O + O2 | - |
Homo sapiens | (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2 | - |
? | |
| p-tyramine + H2O + O2 | - |
Rattus norvegicus | (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MAO-A | - |
Rattus norvegicus |
| MAO-B | - |
Homo sapiens |
| MAO-B | - |
Rattus norvegicus |
| monoamine oxidase A | - |
Rattus norvegicus |
| monoamine oxidase B | - |
Homo sapiens |
| monoamine oxidase B | - |
Rattus norvegicus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
