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Literature summary for 1.4.3.25 extracted from

  • Gau, A.E.; Heindl, A.; Nodop, A.; Kahmann, U.; Pistorius, E.K.
    L-amino acid oxidases with specificity for basic L-amino acids in cyanobacteria (2007), Z. Naturforsch. C, 62, 273-284.
    View publication on PubMed
Search for more literature for 1.4.3.25

Inhibitors

Inhibitors Comment Organism Structure
Ca2+
-
 Synechococcus cedorum
Ca2+
-
 Synechococcus elongatus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3
-
 L-arginine pH not specified in the publication, temperature not specified in the publication Synechococcus elongatus
4
-
 L-arginine pH not specified in the publication, temperature not specified in the publication Synechococcus cedorum
5
-
 L-arginine pH not specified in the publication, temperature not specified in the publication Synechococcus elongatus

Localization

Localization Comment Organism GeneOntology No. Textmining
periplasm 40-60% of total activity Synechococcus cedorum
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arginine + H2O + O2 Synechococcus elongatus
-
 5-guanidino-2-oxopentanoate + NH3 + H2O2
-
 ?
L-arginine + H2O + O2 Synechococcus cedorum
-
 5-guanidino-2-oxopentanoate + NH3 + H2O2
-
 ?
L-arginine + H2O + O2 Synechococcus cedorum PCC 6908
-
 5-guanidino-2-oxopentanoate + NH3 + H2O2
-
 ?
L-arginine + H2O + O2 Synechococcus elongatus PCC 7942
-
 5-guanidino-2-oxopentanoate + NH3 + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Synechococcus cedorum
-
-
-
Synechococcus cedorum PCC 6908
-
-
-
Synechococcus elongatus
-
-
-
Synechococcus elongatus P72346
-
-
Synechococcus elongatus PCC 7942
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O + O2
-
 Synechococcus elongatus 5-guanidino-2-oxopentanoate + NH3 + H2O2
-
 ?
L-arginine + H2O + O2
-
 Synechococcus cedorum 5-guanidino-2-oxopentanoate + NH3 + H2O2
-
 ?
L-arginine + H2O + O2
-
 Synechococcus cedorum PCC 6908 5-guanidino-2-oxopentanoate + NH3 + H2O2
-
 ?
L-arginine + H2O + O2
-
 Synechococcus elongatus PCC 7942 5-guanidino-2-oxopentanoate + NH3 + H2O2
-
 ?
L-histidine + H2O + O2 less than 2% of the activity with L-arginine Synechococcus elongatus 2-oxohistidine + NH3 + H2O2
-
 ?
L-histidine + H2O + O2 less than 2% of the activity with L-arginine Synechococcus cedorum 2-oxohistidine + NH3 + H2O2
-
 ?
L-histidine + H2O + O2 less than 2% of the activity with L-arginine Synechococcus cedorum PCC 6908 2-oxohistidine + NH3 + H2O2
-
 ?
L-histidine + H2O + O2 less than 2% of the activity with L-arginine Synechococcus elongatus PCC 7942 2-oxohistidine + NH3 + H2O2
-
 ?
L-lysine + H2O + O2 73% of the activity with L-arginine Synechococcus elongatus 2-oxolysine + NH3 + H2O2
-
 ?
L-lysine + H2O + O2 81% of the activity with L-arginine Synechococcus cedorum 2-oxolysine + NH3 + H2O2
-
 ?
L-lysine + H2O + O2 82% of the activity with L-arginine Synechococcus elongatus 2-oxolysine + NH3 + H2O2
-
 ?
L-lysine + H2O + O2 81% of the activity with L-arginine Synechococcus cedorum PCC 6908 2-oxolysine + NH3 + H2O2
-
 ?
L-lysine + H2O + O2 82% of the activity with L-arginine Synechococcus elongatus PCC 7942 2-oxolysine + NH3 + H2O2
-
 ?
L-ornithine + H2O + O2 28% of the activity with L-arginine Synechococcus elongatus 2-oxoornithine + NH3 + H2O2
-
 ?
L-ornithine + H2O + O2 35% of the activity with L-arginine Synechococcus cedorum 2-oxoornithine + NH3 + H2O2
-
 ?
L-ornithine + H2O + O2 46% of the activity with L-arginine Synechococcus elongatus 2-oxoornithine + NH3 + H2O2
-
 ?
L-ornithine + H2O + O2 35% of the activity with L-arginine Synechococcus cedorum PCC 6908 2-oxoornithine + NH3 + H2O2
-
 ?
L-ornithine + H2O + O2 28% of the activity with L-arginine Synechococcus elongatus PCC 7942 2-oxoornithine + NH3 + H2O2
-
 ?

Cofactor

Cofactor Comment Organism Structure
FAD evaluation of the binding site Synechococcus elongatus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.1
-
 pH not specified in the publication, temperature not specified in the publication Synechococcus elongatus Ca2+
1.1
-
 pH not specified in the publication, temperature not specified in the publication Synechococcus cedorum Ca2+
1.6
-
 pH not specified in the publication, temperature not specified in the publication Synechococcus elongatus Ca2+