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Literature summary for 1.4.3.21 extracted from

  • Jeon, H.B.; Jang, Y.
    Reversible inactivation of bovine plasma amine oxidase by cysteamine and related analogs (2010), Biochem. Biophys. Res. Commun., 403, 442-446.
    View publication on PubMed
Search for more literature for 1.4.3.21

Inhibitors

Inhibitors Comment Organism Structure
2-(methylamino)ethanethiol reversible inhibition Bos taurus
2-(methylthio)ethylamine weak irreversible inhibitor Bos taurus
3-aminopropanethiol reversible inhibition Bos taurus
cysteamine reversible inhibition Bos taurus
additional information not inhibited by 2-aminoethanol and 2-(N,N-dimethylamino)ethanethiol Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzylamine + H2O + O2
-
 Bos taurus benzaldehyde + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
EC 1.4.3.6 formerly Bos taurus
PAO
-
 Bos taurus
quinone-dependent amine oxidase
-
 Bos taurus

Cofactor

Cofactor Comment Organism Structure
2,4,5-trihydroxyphenylalanine quinone
-
 Bos taurus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0125
-
 in 100 mM potassium phosphate buffer, pH 7.2, at 30°C Bos taurus cysteamine
0.3
-
 in 100 mM potassium phosphate buffer, pH 7.2, at 30°C Bos taurus 3-aminopropanethiol
1.3
-
 in 100 mM potassium phosphate buffer, pH 7.2, at 30°C Bos taurus 2-(methylthio)ethylamine
5
-
 in 100 mM potassium phosphate buffer, pH 7.2, at 30°C Bos taurus 2-(methylamino)ethanethiol