Cloned (Comment) | Organism |
---|---|
expressed in COS-1 cells | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | clorgyline and deprenyl do not significantly inhibit the activities | Rattus norvegicus | |
Semicarbazide | causes significant decreases in the oxidative deamination activity of four among the five substrates catalyzed by SSAO | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | O08590 | nine-week-old male Wistar rats | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00015 | - |
substrate benzylamine, at low substrate concentration | Rattus norvegicus |
0.00023 | - |
substrate beta-phenylethylamine, at low substrate concentration | Rattus norvegicus |
0.00025 | - |
substrate tyramine, at low substrate concentration | Rattus norvegicus |
0.00078 | - |
substrate 1-methylhistamine, at low substrate concentration | Rattus norvegicus |
0.00108 | - |
substrate tyramine, at high substrate concentration | Rattus norvegicus |
0.00136 | - |
substrate beta-phenylethylamine, at high substrate concentration | Rattus norvegicus |
0.00165 | - |
substrate 1-methylhistamine, at high substrate concentration | Rattus norvegicus |
0.00193 | - |
substrate benzylamine, at high substrate concentration | Rattus norvegicus |
0.00388 | - |
substrate serotonin, at high substrate concentration | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-methylhistamine + O2 + H2O | - |
Rattus norvegicus | ? | - |
? | |
benzylamine + O2 + H2O | - |
Rattus norvegicus | benzaldehyde + NH3 + H2O2 | - |
? | |
beta-phenylethylamine + O2 + H2O | - |
Rattus norvegicus | beta-phenylethanal + NH3 + H2O2 | - |
? | |
serotonin + O2 + H2O | - |
Rattus norvegicus | (5-hydroxy-1H-indol-3yl)acetaldehyde + NH3 + H2O2 | - |
? | |
tyramine + O2 + H2O | - |
Rattus norvegicus | 4-hydroxyphenylethanal + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
semicarbazide-sensitive amine oxidase | - |
Rattus norvegicus |
SSAO | - |
Rattus norvegicus |