Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.4.3.2 extracted from

  • Weller, D.
    L-Amino acid oxidase (snake venom) (1971), Methods Enzymol., 17B, 597-600.
No PubMed abstract available
Search for more literature for 1.4.3.2

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Crotalus adamanteus

Inhibitors

Inhibitors Comment Organism Structure
additional information good substrates, not poor substrates are inhibitors; substrate inhibition Crotalus adamanteus

Metals/Ions

Metals/Ions Comment Organism Structure
Cl- favors reaction Crotalus adamanteus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
130000
-
-
 Crotalus adamanteus

Organism

Organism UniProt Comment Textmining
Crotalus adamanteus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein 2-5% carbohydrate, including sialic acid Crotalus adamanteus

Purification (Commentary)

Purification (Comment) Organism
-
 Crotalus adamanteus

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Crotalus adamanteus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Crotalus adamanteus

Storage Stability

Storage Stability Organism
0-5°C, crystalline suspension in water, pH 7.2, stable for several months Crotalus adamanteus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glycine + H2O + O2 low activity Crotalus adamanteus glyoxylate + NH3 + H2O2
-
 ?
L-amino acid + H2O + O2
-
 Crotalus adamanteus 2-oxo acid + NH3 + H2O2
-
 ?
L-aspartic acid + H2O + O2 low activity Crotalus adamanteus oxaloacetate + NH3 + H2O2
-
 ?
L-glutamic acid + H2O + O2 low activity Crotalus adamanteus 2-oxoglutarate + NH3 + H2O2
-
 ?
L-leucine + H2O + O2 high reaction rate Crotalus adamanteus 4-methyl-2-oxopentanoic acid + NH3 + H2O2
-
 ?
L-lysine + H2O + O2 low activity Crotalus adamanteus 6-amino-2-oxohexanoic acid + NH3 + H2O2
-
 ?
L-methionine + H2O + O2 high reaction rate Crotalus adamanteus 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
 ?
L-phenylalanine + H2O + O2 high reaction rate Crotalus adamanteus phenylpyruvate + NH3 + H2O2
-
 ?
L-serine + H2O + O2 low activity Crotalus adamanteus 2-oxo-3-hydroxypropionic acid + NH3 + H2O2
-
 ?
L-threonine + H2O + O2 low activity Crotalus adamanteus 2-oxo-3-hydroxybutanoic acid + NH3 + H2O2
-
 ?
L-tryptophan + H2O + O2 high reaction rate Crotalus adamanteus indole-3-pyruvate + NH3 + H2O2
-
 ?
L-tyrosine + H2O + O2
-
 Crotalus adamanteus p-hydroxyphenylpyruvate + NH3 + H2O2
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 L-leucine Crotalus adamanteus

pH Stability

pH Stability pH Stability Maximum Comment Organism
additional information
-
 slow reversible and temperature-dependent transition to an inactive form under alkaline conditions Crotalus adamanteus

Cofactor

Cofactor Comment Organism Structure
FAD 2 mol of FAD per mol of enzyme Crotalus adamanteus