Application | Comment | Organism |
---|---|---|
medicine | the enzyme severely inhibits growth of cancer cells but shows relatively low cytotoxicity fo normal cells | Trichoderma viride |
Cloned (Comment) | Organism |
---|---|
expressed in Streptomyces lividans strain TK24 | Trichoderma viride |
Crystallization (Comment) | Organism |
---|---|
hanging drop vapor diffusion method, using 0.1M HEPES-NaOH (pH 7.6), 2% (w/v) PEG-400 and 1.8 M ammonium sulfate | Trichoderma viride |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lysine + O2 + H2O | Trichoderma viride | - |
6-amino-2-oxohexanoate + NH3 + H2O2 | - |
? | |
L-lysine + O2 + H2O | Trichoderma viride Y244-2 | - |
6-amino-2-oxohexanoate + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trichoderma viride | - |
- |
- |
Trichoderma viride Y244-2 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
DEAE-Toyopearl 650M column chromatography | Trichoderma viride |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + O2 + H2O | 6.3% activity compared to L-lysine | Trichoderma viride | 5-guanidino-2-oxopentanoate + NH3 + H2O2 | - |
? | |
L-arginine + O2 + H2O | 6.3% activity compared to L-lysine | Trichoderma viride Y244-2 | 5-guanidino-2-oxopentanoate + NH3 + H2O2 | - |
? | |
L-lysine + O2 + H2O | - |
Trichoderma viride | 6-amino-2-oxohexanoate + NH3 + H2O2 | - |
? | |
L-lysine + O2 + H2O | 100% activity | Trichoderma viride | 6-amino-2-oxohexanoate + NH3 + H2O2 | - |
? | |
L-lysine + O2 + H2O | - |
Trichoderma viride Y244-2 | 6-amino-2-oxohexanoate + NH3 + H2O2 | - |
? | |
L-lysine + O2 + H2O | 100% activity | Trichoderma viride Y244-2 | 6-amino-2-oxohexanoate + NH3 + H2O2 | - |
? | |
L-ornithine + O2 + H2O | 18.3% activity compared to L-lysine | Trichoderma viride | 5-amino-2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
L-ornithine + O2 + H2O | 18.3% activity compared to L-lysine | Trichoderma viride Y244-2 | 5-amino-2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
L-phenylalanine + O2 + H2O | 1.7% activity compared to L-lysine | Trichoderma viride | phenylpyruvate + NH3 + H2O2 | - |
? | |
L-phenylalanine + O2 + H2O | 1.7% activity compared to L-lysine | Trichoderma viride Y244-2 | phenylpyruvate + NH3 + H2O2 | - |
? | |
L-tyrosine + O2 + H2O | 1.4% activity compared to L-lysine | Trichoderma viride | 4-hydroxyphenylpyruvate + NH3 + H2O2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 56000, SDS-PAGE | Trichoderma viride |
Synonyms | Comment | Organism |
---|---|---|
L-lysine alpha-oxidase | - |
Trichoderma viride |
LysOx | - |
Trichoderma viride |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
- |
Trichoderma viride |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Trichoderma viride |