Literature summary for 1.4.3.13 extracted from

Behmoaras, J.; Slove, S.; Seve, S.; Vranckx, R.; Sommer, P.; Jacob, M.P.
Differential expression of lysyl oxidases LOXL1 and LOX during growth and aging suggests specific roles in elastin and collagen fiber remodeling in rat aorta (2008), Rejuvenation Res., 11, 883-889.

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Cloned(Commentary)

Cloned (Comment)	Organism
genes and isozymes LOXL1 and LOX, detailed expression analysis in aorta during growth and development, overview	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	-	Rattus norvegicus	-	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	LOU and Brown-Norway rats, male inbred BN/Rij rats, two inbred strains with different susceptibilities to arterial fragility, genes and isozymes LOXL1 and LOX	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
aorta	different spatial and temporal expression of LOX and LOXL1 during growth and aging, expression analysis of LOXL1 and LOX in the aorta during the development, growth, and aging of LOU rats, overview	Rattus norvegicus	-
additional information	high aortic LOX expression early in the development, i.e. embryonic day 15, followed by a drastic reduction in adulthood, whereas LOXL1 is mainly detectable in the intima and media and is expressed throughout life in the LOU rat	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
LOX	-	Rattus norvegicus
LOXL1	-	Rattus norvegicus
lysyl oxidase-like	-	Rattus norvegicus
lysyl oxidases	-	Rattus norvegicus

General Information

General Information	Comment	Organism
physiological function	role for lysyl oxidase-like, LOXL1, in adult elastin synthesis and a role for its isoform, lysyl oxidase, LOX, in the synthesis of both collagens and elastin during development. Specific roles for LOX and LOXL1 in the synthesis and remodeling of elastic and collagen fibers, overview	Rattus norvegicus

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Release 2023.1 (January 2023)