Activating Compound | Comment | Organism | Structure |
---|---|---|---|
transforming growth factor beta | increases LOX expression and activity | Mus musculus |
Application | Comment | Organism |
---|---|---|
medicine | LOX could play a key role in vascular homeostasis and, hence, it emerges as a new player in cardiovascular diseases | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
homocysteine | - |
Mus musculus | |
low-density lipoprotein | decreases lysyl oxidase mRNA levels in endothelial cells | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | dependent | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cardiovascular system | - |
Mus musculus | - |
coronary artery | - |
Mus musculus | - |
endothelium | - |
Mus musculus | - |
fibroblast | - |
Mus musculus | - |
vascular smooth muscle cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
peptidyl-L-lysyl-peptide + O2 + H2O | - |
Mus musculus | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LOX | - |
Mus musculus |
lysyl oxidase | - |
Mus musculus |