Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Candidatus Cloacimonas acidaminovorans |
Protein Variants | Comment | Organism |
---|---|---|
E310G | the mutant exhibits activity towards (S)-beta-aminobutyric acid, beta-alanine, (R)-beta-homoserine, (R)-beta-homomethionine, (S)-beta-homoglutamine, (R)-beta-phenylalanine, and (S)-beta-homolysine | Candidatus Cloacimonas acidaminovorans |
E310G/A314Y | the mutant exhibits activity towards (S)-beta-aminobutyric acid, beta-alanine, (R)-beta-homoserine, (R)-beta-homomethionine, (S)-beta-homoglutamine, (R)-beta-phenylalanine, and (S)-beta-homolysine | Candidatus Cloacimonas acidaminovorans |
E310S | the mutant exhibits activity towards (S)-beta-aminobutyric acid, beta-alanine, (R)-beta-homoserine, (R)-beta-homomethionine, (S)-beta-homoglutamine, (R)-beta-phenylalanine, and (S)-beta-homolysine | Candidatus Cloacimonas acidaminovorans |
E310S/A314N | the mutant exhibits activity towards (S)-beta-aminobutyric acid, beta-alanine, (R)-beta-homoserine, (R)-beta-homomethionine, (S)-beta-homoglutamine, (R)-beta-phenylalanine, and (S)-beta-homolysine | Candidatus Cloacimonas acidaminovorans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-erythro-3,5-diaminohexanoate + H2O + NADP+ | Candidatus Cloacimonas acidaminovorans | - |
(S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candidatus Cloacimonas acidaminovorans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-erythro-3,5-diaminohexanoate + H2O + NADP+ | - |
Candidatus Cloacimonas acidaminovorans | (S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+ | - |
? | |
additional information | the enzyme barely shows any activity towards (S)-beta-aminobutyric acid, beta-alanine, (R)-beta-homoserine, (R)-beta-homomethionine, (S)-beta-homoglutamine, (R)-beta-phenylalanine, and (S)-beta-homolysine | Candidatus Cloacimonas acidaminovorans | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3,5-DAHDH | - |
Candidatus Cloacimonas acidaminovorans |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Candidatus Cloacimonas acidaminovorans |