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Literature summary for 1.4.1.9 extracted from

  • Oki, T.; Shirai, M.
    Antitumor activities of bacterial leucine dehydrogenase and glutaminase A (1973), FEBS Lett., 33, 286-288.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Lysinibacillus sphaericus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Leu + H2O + NAD+
-
Lysinibacillus sphaericus 4-methyl-2-oxopentanoate + NH3 + NADH
-
r
additional information antitumor activity, the enzyme is highly inhibitory to Ehrlich ascites carcinoma cells Lysinibacillus sphaericus ?
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Lysinibacillus sphaericus
NADH
-
Lysinibacillus sphaericus