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Literature summary for 1.4.1.3 extracted from

  • Kravos, M.; Malesic, I.
    Changes in leukocyte Glutamate Dehydrogenase activity in alcoholics upon break in alcohol consumption (2009), Clin. Biochem., 43, 272-277.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
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Homo sapiens
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leukocyte
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Homo sapiens
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Synonyms

Synonyms Comment Organism
GLDH
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Homo sapiens
glutamate dehydrogenase
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Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Homo sapiens

General Information

General Information Comment Organism
physiological function influence of alcohol on leukocyte GLDH activity, its diagnostic value, influence on metabolism and cells toxicity is analysed. Examination is conducted in 238 alcoholics and in 244 healthy persons. A fast increase of leukocyte GLDH activity after break in alcohol consumption is found. After 24 hours, activity increases by 21.8% (median 31.6%), after seven days by 33% (median 52%), yet after a short interval since last alcohol intake (up to 48 hours), it increases by 32% (median 36%) Homo sapiens