Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Bos taurus | |
GTP | - |
Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Bos taurus | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+ | compulsory order mechanism at pH 8.8 | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00076 | - |
activity in liver nuclei, cofactor NADH | Bos taurus |
0.0028 | - |
activity in liver mitochondria, cofactor NADH | Bos taurus |
4.8 | - |
enzyme purified from liver nuclei | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate + H2O + NAD(P)+ | rate of glutamate synthesis is several-fold higher than the rate for the reverse reaction | Bos taurus | 2-oxoglutarate + NH3 + NAD(P)H | - |
r |