BRENDA - Enzyme Database
show all sequences of 1.4.1.24

Genome-wide identification, domain architectures and phylogenetic analysis provide new insights into the early evolution of shikimate pathway in prokaryotes

Zhi, X.Y.; Yao, J.C.; Li, H.W.; Huang, Y.; Li, W.J.; Mol. Phylogenet. Evol. 75, 154-164 (2014)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Streptomyces griseus
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Stigmatella aurantiaca
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Streptomyces scabiei
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Frankia casuarinae
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Streptomyces griseus NBRC 13350
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Streptomyces scabiei 87.22
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Streptomyces griseus
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Stigmatella aurantiaca
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Streptomyces scabiei
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Frankia casuarinae
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Streptomyces griseus NBRC 13350
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Streptomyces scabiei 87.22
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Frankia casuarinae
-
-
-
Stigmatella aurantiaca
-
-
-
Streptomyces griseus
-
-
-
Streptomyces griseus NBRC 13350
-
-
-
Streptomyces scabiei
-
-
-
Streptomyces scabiei 87.22
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Streptomyces griseus
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Stigmatella aurantiaca
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Streptomyces scabiei
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Frankia casuarinae
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Streptomyces griseus NBRC 13350
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Streptomyces scabiei 87.22
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Streptomyces griseus
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Stigmatella aurantiaca
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Streptomyces scabiei
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Frankia casuarinae
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Streptomyces griseus NBRC 13350
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Streptomyces scabiei 87.22
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
aroB2
-
Frankia casuarinae
aroB2
-
Stigmatella aurantiaca
aroB2
-
Streptomyces griseus
aroB2
-
Streptomyces scabiei
DHQ synthase
-
Frankia casuarinae
DHQ synthase
-
Stigmatella aurantiaca
DHQ synthase
-
Streptomyces griseus
DHQ synthase
-
Streptomyces scabiei
DHQS
-
Frankia casuarinae
DHQS
-
Stigmatella aurantiaca
DHQS
-
Streptomyces griseus
DHQS
-
Streptomyces scabiei
type II 3-dehydroquinate synthase
-
Frankia casuarinae
type II 3-dehydroquinate synthase
-
Stigmatella aurantiaca
type II 3-dehydroquinate synthase
-
Streptomyces griseus
type II 3-dehydroquinate synthase
-
Streptomyces scabiei
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Frankia casuarinae
NAD+
-
Stigmatella aurantiaca
NAD+
-
Streptomyces griseus
NAD+
-
Streptomyces scabiei
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Frankia casuarinae
NAD+
-
Stigmatella aurantiaca
NAD+
-
Streptomyces griseus
NAD+
-
Streptomyces scabiei
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Streptomyces griseus
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Stigmatella aurantiaca
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Streptomyces scabiei
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Frankia casuarinae
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Streptomyces griseus NBRC 13350
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
Streptomyces scabiei 87.22
-
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Streptomyces griseus
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Stigmatella aurantiaca
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Streptomyces scabiei
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Frankia casuarinae
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Streptomyces griseus NBRC 13350
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
Streptomyces scabiei 87.22
-
3-dehydroquinate + NH3 + NADH + H+
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Streptomyces griseus
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Stigmatella aurantiaca
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Streptomyces scabiei
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Frankia casuarinae
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Streptomyces griseus NBRC 13350
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
743314
Streptomyces scabiei 87.22
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Streptomyces griseus
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Stigmatella aurantiaca
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Streptomyces scabiei
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Frankia casuarinae
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Streptomyces griseus NBRC 13350
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
743314
Streptomyces scabiei 87.22
3-dehydroquinate + NH3 + NADH + H+
-
-
-
?
Other publictions for EC 1.4.1.24
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743314
Zhi
Genome-wide identification, d ...
Frankia casuarinae, Stigmatella aurantiaca, Streptomyces griseus, Streptomyces griseus NBRC 13350, Streptomyces scabiei, Streptomyces scabiei 87.22
Mol. Phylogenet. Evol.
75
154-164
2014
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-
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-
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-
-
-
-
-
12
-
6
-
-
-
-
-
-
-
-
12
-
16
-
-
-
-
-
-
-
4
-
-
-
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-
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4
-
-
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-
-
-
-
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12
-
-
-
-
-
-
-
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12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
718845
Morar
Structure of 2-amino-3,7-dideo ...
Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661
Biochemistry
46
10562-10571
2007
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
2
-
2
-
-
-
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-
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-
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2
-
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-
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-
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-
-
718838
White
L-Aspartate semialdehyde and a ...
Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661
Biochemistry
43
7618-7627
2004
-
-
1
-
-
-
-
-
-
-
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5
-
-
1
-
-
-
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2
-
1
-
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-
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-
1
-
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-
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-
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-
-
-
-
-
-
1
-
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-
2
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