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Literature summary for 1.4.1.2 extracted from

  • Pathan, E.K.; Ghormade, V.; Panwar, S.L.; Prasad, R.; Deshpande, M.V.
    Molecular studies of NAD- and NADP-glutamate dehydrogenases decipher the conundrum of yeast-hypha dimorphism in zygomycete Benjaminiella poitrasii (2019), FEMS Yeast Res., 19, foz074 .
    View publication on PubMed
Search for more literature for 1.4.1.2

Cloned(Commentary)

Cloned (Comment) Organism
gene gdh2, single copy gene, DNA and amino acid sequence determination and analysis, phylogenetic analysis, quantitative RT-PCR enzyme expression analysis, recombinant expression in the monomorphic mutant Y-5 of Benjaminiella poitrasii and in human-pathogenic, non-dimorphic Candida glabrata Benjaminiella poitrasii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-glutamate + H2O + NAD+ Benjaminiella poitrasii
-
 2-oxoglutarate + NH3 + NADH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Benjaminiella poitrasii A0A076L6G6
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate + H2O + NAD+
-
 Benjaminiella poitrasii 2-oxoglutarate + NH3 + NADH + H+
-
 r

Synonyms

Synonyms Comment Organism
BpNADGDH
-
 Benjaminiella poitrasii
GDH2
-
 Benjaminiella poitrasii
NAD-dependent glutamate dehydrogenase
-
 Benjaminiella poitrasii

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
 assay at room temperature Benjaminiella poitrasii

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Benjaminiella poitrasii
NADH
-
 Benjaminiella poitrasii

General Information

General Information Comment Organism
evolution BpNADGDH gives over 65% identity scores with fungal NAD-dependent GDHs Benjaminiella poitrasii