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Literature summary for 1.4.1.2 extracted from

  • Rosso, L.; Marques, A.C.; Reichert, A.S.; Kaessmann, H.
    Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection (2008), PLoS Genet., 4, e1000150.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Chlorocebus sabaeus 5737
-
cytoplasm
-
Pan troglodytes 5737
-
cytoplasm
-
Gorilla gorilla 5737
-
cytoplasm
-
Pongo pygmaeus 5737
-
cytoplasm
-
Symphalangus syndactylus 5737
-
cytoplasm GLUD1 Homo sapiens 5737
-
mitochondrion
-
Chlorocebus sabaeus 5739
-
mitochondrion
-
Pan troglodytes 5739
-
mitochondrion
-
Gorilla gorilla 5739
-
mitochondrion
-
Pongo pygmaeus 5739
-
mitochondrion
-
Symphalangus syndactylus 5739
-
mitochondrion GLUD2 is specifically targeted to mitochondria, whereas GLUD1 is localized in mitochondria and cytoplasm Homo sapiens 5739
-

Organism

Organism UniProt Comment Textmining
Chlorocebus sabaeus Q64H33 fragment
-
Gorilla gorilla B5AAK3 fragment
-
Homo sapiens
-
-
-
Pan troglodytes B5AAJ9 fragment
-
Pongo pygmaeus B5AAK0 fragment
-
Symphalangus syndactylus B5AAK1 fragment; also named Symphalangus syndactylus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate + H2O + NAD+
-
Homo sapiens 2-oxoglutarate + NH3 + NADH + H+
-
?
L-glutamate + H2O + NAD+
-
Chlorocebus sabaeus 2-oxoglutarate + NH3 + NADH + H+
-
?
L-glutamate + H2O + NAD+
-
Pan troglodytes 2-oxoglutarate + NH3 + NADH + H+
-
?
L-glutamate + H2O + NAD+
-
Gorilla gorilla 2-oxoglutarate + NH3 + NADH + H+
-
?
L-glutamate + H2O + NAD+
-
Pongo pygmaeus 2-oxoglutarate + NH3 + NADH + H+
-
?
L-glutamate + H2O + NAD+
-
Symphalangus syndactylus 2-oxoglutarate + NH3 + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
GLUD1 isozyme Homo sapiens
GLUD1 isozyme Chlorocebus sabaeus
GLUD1 isozyme Pan troglodytes
GLUD1 isozyme Gorilla gorilla
GLUD1 isozyme Pongo pygmaeus
GLUD1 isozyme Symphalangus syndactylus
GLUD2 isozyme Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens
NAD+
-
Chlorocebus sabaeus
NAD+
-
Pan troglodytes
NAD+
-
Gorilla gorilla
NAD+
-
Pongo pygmaeus
NAD+
-
Symphalangus syndactylus