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Literature summary for 1.4.1.2 extracted from
- Purification and properties of NAD-dependent glutamate dehydrogenase from Phycomyces spores (1988), J. Gen. Microbiol., 134, 1597-1601.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ADP | stimulation | Phycomyces blakesleeanus |  |
| AMP | required | Phycomyces blakesleeanus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | weak | Phycomyces blakesleeanus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 54000 | - |
2 * 54000, SDS-PAGE | Phycomyces blakesleeanus |
| 98000 | - |
gel filtration | Phycomyces blakesleeanus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Phycomyces blakesleeanus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Phycomyces blakesleeanus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-glutamate + H2O + NAD+ | - |
Phycomyces blakesleeanus | 2-oxoglutarate + NH3 + NADH + H+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 54000, SDS-PAGE | Phycomyces blakesleeanus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 8.5 | reductive amination | Phycomyces blakesleeanus |
| 9 | - |
oxidative deamination | Phycomyces blakesleeanus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Phycomyces blakesleeanus | |
| NADH | - |
Phycomyces blakesleeanus | |
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