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Literature summary for 1.4.1.14 extracted from

  • Hummelt, G.; Mora, J.
    NADH-dependent glutamate synthase and nitrogen metabolism in Neurospora crassa (1980), Biochem. Biophys. Res. Commun., 92, 127-133.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
azaserine complete inhibition Neurospora crassa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-glutamine + 2-oxoglutarate + NADH Neurospora crassa glutamine synthetase/glutamate synthase pathway for ammonia assimilation is fafavoured by growth at low concentrations of ammonia glutamate + NAD+
-
?
L-glutamine + 2-oxoglutarate + NADH Neurospora crassa am-1 glutamine synthetase/glutamate synthase pathway for ammonia assimilation is fafavoured by growth at low concentrations of ammonia glutamate + NAD+
-
?

Organism

Organism UniProt Comment Textmining
Neurospora crassa
-
-
-
Neurospora crassa am-1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
136fold purification Neurospora crassa

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.76
-
-
Neurospora crassa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamine + 2-oxoglutarate + NADH
-
Neurospora crassa L-glutamate + NAD+
-
?
L-glutamine + 2-oxoglutarate + NADH
-
Neurospora crassa am-1 L-glutamate + NAD+
-
?
L-glutamine + 2-oxoglutarate + NADH glutamine synthetase/glutamate synthase pathway for ammonia assimilation is fafavoured by growth at low concentrations of ammonia Neurospora crassa glutamate + NAD+
-
?
L-glutamine + 2-oxoglutarate + NADH glutamine synthetase/glutamate synthase pathway for ammonia assimilation is fafavoured by growth at low concentrations of ammonia Neurospora crassa am-1 glutamate + NAD+
-
?

Cofactor

Cofactor Comment Organism Structure
NADH
-
Neurospora crassa