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Literature summary for 1.4.1.1 extracted from

  • Jeong, J.A.; Baek, E.Y.; Kim, S.W.; Choi, J.S.; Oh, J.I.
    Regulation of the ald gene encoding alanine dehydrogenase by AldR in Mycobacterium smegmatis (2013), J. Bacteriol., 195, 3610-3620 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Mycolicibacterium smegmatis
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Expression

Organism Comment Expression
Mycolicibacterium smegmatis regulatory gene AldR serves as both activator and repressor for the regulation of ald gene expression, depending on the presence or absence of L-alanine. The purified AldR protein exists as a homodimer in the absence of L-alanine, while it adopts the quaternary structure of a homohexamer in the presence of L-alanine. The binding affinity of AldR for the ald control region is significantly increased by L-alanine additional information