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Literature summary for 1.3.99.5 extracted from
- Steroid 5-alpha-reductase type 2 (SRD5A2) V89L and A49T polymorphisms and sporadic prostate cancer risk: a meta-analysis (2013), Mol. Biol. Rep., 40, 3597-3608.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| A49T | the mutation is likely to have a contribution to prostate cancer development | Homo sapiens |
| V89L | the mutation is not likely to have a major contribution to prostate cancer development | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| testosterone + reduced acceptor | Homo sapiens | - |
5alpha-dihydrotestosterone + acceptor | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| prostate cancer cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| testosterone + reduced acceptor | - |
Homo sapiens | 5alpha-dihydrotestosterone + acceptor | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SRD5A2 | - |
Homo sapiens |
| steroid 5-alpha-reductase type 2 | - |
Homo sapiens |
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