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Literature summary for 1.3.99.23 extracted from
- An RNAi-based genetic screen for oxidative stress resistance reveals retinol saturase as a mediator of stress resistance (2007), Free Radic. Biol. Med., 43, 781-788.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in NIH-3T3 cells and HEK-293 cells | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | a short hairpin RNA targeting retinol saturase strongly protects cells from tert-butylhydroperoxide and H2O2 by specifically reducing the expression of retinol saturase | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q64FW2 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| all-trans-retinol + reduced acceptor | - |
Mus musculus | all-trans-13,14-dihydroretinol + acceptor | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| retinol saturase | regulates retinoid metabolism and sensitivity to oxidative stress | Mus musculus |
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Release 2023.1 (January 2023)
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