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Literature summary for 1.3.8.4 extracted from

  • Daschner, K.; Couee, I.; Binder, S.
    The mitochondrial isovaleryl-coenzyme A dehydrogenase of Arabidopsis oxidizes intermediates of leucine and valine catabolism (2001), Plant Physiol., 126, 601-612.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.8.4

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Arabidopsis thaliana

Inhibitors

Inhibitors Comment Organism Structure
sucrose inhibits promoter activity Arabidopsis thaliana

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.05
-
 isovaleryl-CoA
-
 Arabidopsis thaliana
0.5
-
 isobutyryl-CoA
-
 Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Arabidopsis thaliana 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43000
-
 ? * 43000, SDS-PAGE Arabidopsis thaliana
87000 107000 gel filtration Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isovaleryl-CoA + acceptor Arabidopsis thaliana
-
 3-methylcrotonyl-CoA + reduced acceptor
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-methyl-hexanoyl-CoA + acceptor 4% relative activity to isovaleryl-CoA Arabidopsis thaliana 2-methylhex-2-enoyl-CoA + reduced acceptor
-
 ?
2-methylpalmitoyl-CoA + acceptor 7% relative activity to isovaleryl-CoA Arabidopsis thaliana 2-methylhexadec-2-enoyl-CoA + reduced acceptor
-
 ?
2-methylpalmitoyl-CoA + acceptor minor activity Arabidopsis thaliana 2-methylhexadec-2-enoyl-CoA + reduced acceptor
-
 ?
hexanoyl-CoA + acceptor weak activity Arabidopsis thaliana hex-2-enoyl-CoA + reduced acceptor
-
 ?
isobutyryl-CoA + acceptor 20% relative activity to isovaleryl-CoA Arabidopsis thaliana 2-methylpropanoyl-CoA + reduced acceptor
-
 ?
isobutyryl-CoA + acceptor the activity with isobutyryl-CoA implies an additional role of the enzyme in the catabolism of valine Arabidopsis thaliana 2-methylpropanoyl-CoA + reduced acceptor
-
 ?
isovaleryl-CoA + acceptor
-
 Arabidopsis thaliana 3-methylcrotonyl-CoA + reduced acceptor
-
 ?
isovaleryl-CoA + acceptor isovaleryl-CoA is the preferred substrate Arabidopsis thaliana 3-methylcrotonyl-CoA + reduced acceptor
-
 ?
octanoyl-CoA + acceptor 7% relative activity to isovaleryl-CoA Arabidopsis thaliana oct-2-enoyl-CoA + reduced acceptor
-
 ?

Subunits

Subunits Comment Organism
? ? * 43000, SDS-PAGE Arabidopsis thaliana