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Literature summary for 1.3.7.7 extracted from

  • Kopecna, J.; Sobotka, R.; Komenda, J.
    Inhibition of chlorophyll biosynthesis at the protochlorophyllide reduction step results in the parallel depletion of photosystem I and photosystem II in the cyanobacterium Synechocystis PCC 6803 (2013), Planta, 237, 497-508.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information construction of a DELTAchlL strain Synechocystis sp.

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Synechocystis sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protochlorophyllide a + reduced ferredoxin + 2 ATP + 2 H2O Synechocystis sp.
-
chlorophyllide a + oxidized ferredoxin + 2 ADP + 2 phosphate
-
?

Organism

Organism UniProt Comment Textmining
Synechocystis sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protochlorophyllide a + reduced ferredoxin + 2 ATP + 2 H2O
-
Synechocystis sp. chlorophyllide a + oxidized ferredoxin + 2 ADP + 2 phosphate
-
?

Synonyms

Synonyms Comment Organism
dark-operative protochlorophyllide oxidoreductase
-
Synechocystis sp.
DPOR
-
Synechocystis sp.

Cofactor

Cofactor Comment Organism Structure
ATP
-
Synechocystis sp.
Ferredoxin
-
Synechocystis sp.

General Information

General Information Comment Organism
malfunction a strain lacking DPOR contains about 25% of the wild-type level of photosystems PSII and PSI when cultivated under light-activated heterotrophic growth conditions. Deletion of the chlL gene abolishes activity of the DPOR enzyme. Absence of the chlL gene causes a further 20% decrease in Chl content and therefore the resulting (pCER:por)/Dpor/DchlL strain termed SynPORreg reaches only 60-70% of Chl content present in wild-type Synechocystis sp.
metabolism two independent enzymes catalyze the reduction of protochlorophyllide to chlorophyllide, which is the penultimate step in chlorophyll biosynthesis. One is light-dependent NADPH:protochlorophyllide oxidoreductase and the second type is dark-operative protochlorophyllide oxidoreductase Synechocystis sp.