Cloned (Comment) | Organism |
---|---|
gene pebAB, overexpression in Synechococcus sp. strain PCC 7002, from endogenous plasmid pAQ1 under the control of the Synechocystis sp. strain PCC 6803 cpcBA promoter, leads to overproduction of phytochromobilin. Colonies of Synechococcus sp. strain PCC 7002 transformed with the pebAB overexpression cassette mostly exhibit a reddish-brown phenotype | Synechococcus sp. |
Protein Variants | Comment | Organism |
---|---|---|
additional information | because PcyA, EC 1.3.7.5, and PebA utilize the same substrate, biliverdin IXalpha, severe overexpression of pebA can limit the availability of phycocyanobilin, which appears to be required for viability when cells are grown in continuous light, phenotype, overview | Synechococcus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
biliverdin IXalpha + 2 reduced ferredoxin | Synechococcus sp. | - |
(3Z)-phycoerythrobilin + 2 oxidized ferredoxin | - |
? | |
biliverdin IXalpha + 2 reduced ferredoxin | Synechococcus sp. PCC 7335 | - |
(3Z)-phycoerythrobilin + 2 oxidized ferredoxin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Synechococcus sp. | - |
gene pebAB | - |
Synechococcus sp. PCC 7335 | - |
gene pebAB | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
biliverdin IXalpha + 2 reduced ferredoxin | - |
Synechococcus sp. | (3Z)-phycoerythrobilin + 2 oxidized ferredoxin | - |
? | |
biliverdin IXalpha + 2 reduced ferredoxin | (3Z)-phycoerythrobilin is synthesized from biliverdin IXalpha by the sequential actions of two reductases, PebA and PebB | Synechococcus sp. | (3Z)-phycoerythrobilin + 2 oxidized ferredoxin | - |
? | |
biliverdin IXalpha + 2 reduced ferredoxin | - |
Synechococcus sp. PCC 7335 | (3Z)-phycoerythrobilin + 2 oxidized ferredoxin | - |
? | |
biliverdin IXalpha + 2 reduced ferredoxin | (3Z)-phycoerythrobilin is synthesized from biliverdin IXalpha by the sequential actions of two reductases, PebA and PebB | Synechococcus sp. PCC 7335 | (3Z)-phycoerythrobilin + 2 oxidized ferredoxin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PebA | - |
Synechococcus sp. |
PebB | - |
Synechococcus sp. |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Ferredoxin | - |
Synechococcus sp. |
General Information | Comment | Organism |
---|---|---|
evolution | synthesis of linear tetrapyrrole chromophores in cyanobacteria, algae, and plants, ooverview | Synechococcus sp. |