Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
brain | presence of enzymatically active DHODH in many regions of the central nervous system, albeit at different intensities. High levels of both DHODH activity and immunoreactivity are observed in the neocortex, hippocampus, spinal cord and choroid plexus. Lower levels are seen in the cerebellum, and only marginal expression in brain stem | Rattus norvegicus | - |
brain stem | very low enzyme level | Rattus norvegicus | - |
brain stem | very low level both of expression and activity | Rattus norvegicus | - |
central nervous system | regiospecific distribution of DHODH, immunohistochemic analysis, overview | Rattus norvegicus | - |
cerebellum | low enzyme level | Rattus norvegicus | - |
cerebellum | low level both of expression and activity | Rattus norvegicus | - |
cerebral cortex | high enzyme level | Rattus norvegicus | - |
choroid plexus | high level both of expression and activity | Rattus norvegicus | - |
hippocampus | high enzyme level | Rattus norvegicus | - |
hippocampus | high level both of expression and activity | Rattus norvegicus | - |
neocortex | high level both of expression and activity | Rattus norvegicus | - |
neuron | - |
Rattus norvegicus | - |
spinal cord | high level both of expression and activity | Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
DHODH | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
metabolism | DHODH is the fourth enzyme in the biosynthesis of pyrimidines | Rattus norvegicus |