Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.3.5.1 extracted from

  • Dekker, P.B.D.; Hogendoorn, P.C.W.; Kuipers-Dijkshoorn, N.; Prins, F.A.; van Duinen, S.G.; Taschner, P.E.M.; van der Mey, A.G.L.; Cornelisse, C.J.
    SDHD mutations in head and neck paragangliomas result in destabilization of complex II in the mitochondrial respiratory chain with loss of enzymatic activity and abnormal mitochondrial morphology (2003), J. Pathol., 201, 480-486.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
succinate + ubiquinone Homo sapiens
-
fumarate + ubiquinol
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information loss of SDH activity in chief cells is found in the majority, i.e. 90%, of head and neck paragaliomas Homo sapiens
-
myocardium
-
Homo sapiens
-
renal tubule epithelium Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinate + ubiquinone
-
Homo sapiens fumarate + ubiquinol
-
?

Synonyms

Synonyms Comment Organism
SDH
-
Homo sapiens