Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,4-pentadienoyl-CoA | rapid, irreversible | Candida tropicalis | |
3-octynoyl-CoA | irreversible | Candida tropicalis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
75000 | - |
8 * 75000, SDS-PAGE | Candida tropicalis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + O2 | Candida tropicalis | - |
trans-2,3-dehydroacyl-CoA + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida tropicalis | - |
pK 233, inducible by growth on alkanes | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2 | anti-elimination of pro-2R and pro-3R hydrogens of acyl-CoA | Candida tropicalis |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Candida tropicalis |
Storage Stability | Organism |
---|---|
-20°C, pH 7.4, 2 months | Candida tropicalis |
4°C, pH 7.4, 2 months, 20% loss of activity | Candida tropicalis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxoheptadecyldethio-CoA + O2 | - |
Candida tropicalis | ? | - |
? | |
acyl-CoA + O2 | - |
Candida tropicalis | trans-2,3-dehydroacyl-CoA + H2O2 | - |
? | |
palmitoyl-CoA + O2 | - |
Candida tropicalis | 2-trans-hexadecenoyl-CoA + H2O2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
octamer | 8 * 75000, SDS-PAGE | Candida tropicalis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | flavoprotein | Candida tropicalis | |
FAD | 8 mol FAD per mol of enzyme, 1 mol FAD per mol of subunit | Candida tropicalis |