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Literature summary for 1.3.3.4 extracted from

  • Ferreira, G.C.; Dailey, H.A.
    Reconstitution of the two terminal enzymes of the heme biosynthetic pathway into phospholipid vesicles (1987), J. Biol. Chem., 262, 4407-4412.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
phosphatidylcholine from egg and soybean Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00078
-
protoporphyrinogen-IX in phospholipid vesicles Mus musculus
0.002
-
protoporphyrinogen-IX in detergent solution in presence of cardiolipin Mus musculus
0.0056
-
protoporphyrinogen-IX in detergent solution Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protoporphyrinogen-IX + 3 O2 Mus musculus penultimate step of heme and chlorophyll biosynthesis protoporphyrin-IX + 3 H2O2
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protoporphyrinogen-IX + 3 O2
-
Mus musculus protoporphyrin-IX + 3 H2O2
-
?
protoporphyrinogen-IX + 3 O2 penultimate step of heme and chlorophyll biosynthesis Mus musculus protoporphyrin-IX + 3 H2O2
-
?