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Literature summary for 1.3.3.3 extracted from

  • Sinha, A.K.; Anand, S.; Ortel, B.J.; Chang, Y.; Mai, Z.; Hasan, T.; Maytin, E.V.
    Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells (2006), Br. J. Cancer, 95, 485-495.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.3.3

Activating Compound

Activating Compound Comment Organism Structure
methotrexate causes a 3fold accumulation of CPO at both the mRNA and protein levels Homo sapiens

Application

Application Comment Organism
medicine new combination photodynamic therapy approach for certain cancers Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
into vector PCRII-TOPO, transferred into vector pcDNA3.1(-), and transfection of LNCaP cells and Cos-7 cells Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
 Western blot analysis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell
-
 Homo sapiens
-
prostate cancer cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
coproporphyrinogen-III + O2 + 2 H+
-
 Homo sapiens protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
 ?

Synonyms

Synonyms Comment Organism
CPO
-
 Homo sapiens