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Literature summary for 1.3.3.11 extracted from

  • Magnusson, O.T.; Toyama, H.; Saeki, M.; Rojas, A.; Reed, J.C.; Liddington, R.C.; Klinman, J.P.; Schwarzenbacher, R.
    Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone (2004), Proc. Natl. Acad. Sci. USA, 101, 7913-7918.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.3.11

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Klebsiella pneumoniae

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting drop vapor diffusion method Klebsiella pneumoniae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28910
-
 2 * 28910 Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2 Klebsiella pneumoniae synthesis of the pyrroloquinoline quinone (PQQ), that serves as prosthetic group for many bacterial enzymes 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O the product is pyrroloquinoline quinone (PQQ) ?

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae P27505
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2
-
 Klebsiella pneumoniae 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O the product is pyrroloquinoline quinone (PQQ) ?
3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic acid + O2 synthesis of the pyrroloquinoline quinone (PQQ), that serves as prosthetic group for many bacterial enzymes Klebsiella pneumoniae 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + H2O2 + H2O the product is pyrroloquinoline quinone (PQQ) ?

Subunits

Subunits Comment Organism
dimer 2 * 28910 Klebsiella pneumoniae

Synonyms

Synonyms Comment Organism
PqqC
-
 Klebsiella pneumoniae