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Literature summary for 1.3.1.B7 extracted from

  • Parker, J.B.; Walsh, C.T.
    Stereochemical outcome at four stereogenic centers during conversion of prephenate to tetrahydrotyrosine by BacABGF in the bacilysin pathway (2012), Biochemistry, 51, 5622-5632.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.1.B7

Cloned(Commentary)

Cloned (Comment) Organism
-
 Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NADH + H+ Bacillus subtilis
-
 3-[(1R,4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NAD+
-
 ?
(3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NADH + H+ Bacillus subtilis 168
-
 3-[(1R,4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NAD+
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis P39644
-
-
Bacillus subtilis 168 P39644
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bacillus subtilis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NADH + H+
-
 Bacillus subtilis 3-[(1R,4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NAD+
-
 ?
(3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NADH + H+ the enzyme is involved in the biosynthesis of the antibiotic bacilysin Bacillus subtilis 3-[(1R,4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NAD+
-
 ?
(3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NADH + H+
-
 Bacillus subtilis 168 3-[(1R,4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NAD+
-
 ?
(3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NADH + H+ the enzyme is involved in the biosynthesis of the antibiotic bacilysin Bacillus subtilis 168 3-[(1R,4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NAD+
-
 ?

Synonyms

Synonyms Comment Organism
BacG
-
 Bacillus subtilis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Bacillus subtilis

General Information

General Information Comment Organism
physiological function the enzyme is involved in the biosynthesis of the antibiotic bacilysin Bacillus subtilis