Literature summary for 1.3.1.9 extracted from

Oliveira, J.S.; de Sousa, E.H.; de Souza, O.N.; Moreira, I.S.; Santos, D.S.; Basso, L.A.
Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex (2006), Curr. Pharm. Des., 12, 2409-2424.

Search for more literature for 1.3.1.9

Application

Application	Comment	Organism
medicine	tuberculosis, TB, target of anti-tubercular agents	Mycobacterium tuberculosis

Protein Variants

Protein Variants	Comment	Organism
I21V	isoniazid resistance mutant of Mycobacterium tuberculosis enoyl-[acyl-carrier-protein] reductase	Mycobacterium tuberculosis

Inhibitors

Inhibitors	Comment	Organism	Structure
isoniazid	INH, isonicotinic acid hydrazide	Mycobacterium tuberculosis
pentacyano(isoniazid)ferrateII complex	Na3[FeII(CN)5(INH)]*3H2O complex	Mycobacterium tuberculosis

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	-	-	-

Synonyms

Synonyms	Comment	Organism
2-trans-enoyl-ACP (CoA) reductase	-	Mycobacterium tuberculosis
enoyl-[acyl-carrier-protein] reductase	-	Mycobacterium tuberculosis

Cofactor

Cofactor	Comment	Organism	Structure
NADH	-	Mycobacterium tuberculosis

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Release 2023.1 (January 2023)