Cloned (Comment) | Organism |
---|---|
human embryonic kidney cells (293 cell line) are transiently transfected either with an episomal rAOR overexpression vector (pCEP4-rAOR) or control vector (pCEP4). AOR transfected cells produce a 7-8fold higher expression of AOR than control cells | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.213 | - |
(-)-hydroxymethylacylfulvene | pH 7.2, 37°C | Homo sapiens | |
0.243 | - |
(+)-hydroxymethylacylfulvene | pH 7.2, 37°C | Homo sapiens | |
0.465 | - |
(+)-acylfulvene | pH 7.2, 37°C | Homo sapiens | |
0.538 | - |
(-)-acylfulvene | pH 7.2, 37°C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+)-acylfulvene + NADPH | - |
Homo sapiens | ? | - |
? | |
(+)-hydroxymethylacylfulvene + NADPH | - |
Homo sapiens | ? | - |
? | |
(-)-acylfulvene + NADPH | - |
Homo sapiens | ? | - |
? | |
(-)-hydroxymethylacylfulvene + NADPH | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alkenal/one reductase | - |
Homo sapiens |
AOR | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |