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Literature summary for 1.3.1.56 extracted from

  • Barriault, D.; Vedadi, M.; Powlowski, J.; Sylvestre, M.
    cis-2,3-Dihydro-2,3-dihydroxybiphenyl dehydrogenase and cis-1,2-dihydro-1,2-dihydroxynaphathalene dehydrogenase catalyze dehydrogenation of the same range of substrates (1999), Biochem. Biophys. Res. Commun., 260, 181-187.
    View publication on PubMed
Search for more literature for 1.3.1.56

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0039
-
 cis-2,3-dihydro-2,3-dihydroxybiphenyl with 2.5 mM NAD+ Comamonas testosteroni
0.28
-
 cis-1,2-dihydro-1,2-dihydroxynaphthalene with 2.5 mM NAD+ Comamonas testosteroni
1.5
-
 3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl with 2.5 mM NAD+ Comamonas testosteroni

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+ Burkholderia cepacia
-
 3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
 ?
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+ Comamonas testosteroni
-
 3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
 ?
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+ Burkholderia cepacia LB400
-
 3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
 ?
cis-1,2-dihydro-1,2-dihydroxynaphthalene + NAD+ Comamonas testosteroni
-
 ? + NADH
-
 ?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD+ Comamonas testosteroni biphenyl degradation pathway 2,3-dihydroxybiphenyl + NADH
-
 ?

Organism

Organism UniProt Comment Textmining
Burkholderia cepacia
-
-
-
Burkholderia cepacia LB400
-
-
-
Comamonas testosteroni Q46381
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+
-
 Burkholderia cepacia 3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
 ?
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+
-
 Comamonas testosteroni 3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
 ?
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+
-
 Burkholderia cepacia LB400 3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
 ?
cis-1,2-dihydro-1,2-dihydroxynaphthalene + NAD+
-
 Comamonas testosteroni ? + NADH
-
 ?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD+
-
 Comamonas testosteroni 2,3-dihydroxybiphenyl + NADH
-
 ?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD+ biphenyl degradation pathway Comamonas testosteroni 2,3-dihydroxybiphenyl + NADH
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.123
-
 3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl with 2.5 mM NAD+ Comamonas testosteroni
0.38
-
 cis-2,3-dihydro-2,3-dihydroxybiphenyl with 2.5 mM NAD+ Comamonas testosteroni
0.9
-
 cis-1,2-dihydro-1,2-dihydroxynaphthalene with 2.5 mM NAD+ Comamonas testosteroni

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Burkholderia cepacia
NAD+
-
 Comamonas testosteroni