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Literature summary for 1.3.1.38 extracted from

  • Gurvitz, A.
    A C. elegans model for mitochondrial fatty acid synthase II: the longevity-associated gene W09H1.5/mecr-1 encodes a 2-trans-enoyl-thioester reductase (2009), PLoS ONE, 4, e7791.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.1.38

Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae DELTA etr1 cells Caenorhabditis elegans

Protein Variants

Protein Variants Comment Organism
additional information knockdown of MECR-1 resulted in life span extension Caenorhabditis elegans

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Caenorhabditis elegans 5739
-
soluble
-
 Caenorhabditis elegans
-
-

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans O45903
-
-
Caenorhabditis elegans Q9XXC8
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.2
-
 mutant cells over-expressiong MECR-1 Caenorhabditis elegans
3.21
-
 cells overexpressing native Etr1p Caenorhabditis elegans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-trans-hexenoyl-CoA + NADPH
-
 Caenorhabditis elegans ?
-
 ?

Synonyms

Synonyms Comment Organism
MECR-1
-
 Caenorhabditis elegans
mitochondrial 2-trans-enoyl-CoA/ACP reductase
-
 Caenorhabditis elegans
mitochondrial 2-trans-enoyl-thioester reductase
-
 Caenorhabditis elegans

General Information

General Information Comment Organism
malfunction knockdown of MECR-1 resulted in life span extension Caenorhabditis elegans