Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P51857 | - |
- |
Mus musculus | Q8VCX1 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Hep-G2 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
AKR1D1 | - |
Homo sapiens |
AKR1D1 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | chenodeoxycholic acid markedly represses AKR1D1 expression in vitro in human hepatoma Hep-G2 cells, regulation occurs through the mitogen-activated protein kinases/c-Jun Nterminal kinases (MAPK/JNK) signaling pathway | down |
Mus musculus | chenodeoxycholic acid markedly represses AKR1D1 expression, regulation occurs through the mitogen-activated protein kinases/c-Jun Nterminal kinases (MAPK/JNK) signaling pathway | down |
Homo sapiens | cholic acid significantly upregulates AKR1D1 expression in HepG2 cells, regulation occurs through the mitogen-activated protein kinases/c-Jun Nterminal kinases (MAPK/JNK) signaling pathway | up |
Mus musculus | cholic acid significantly upregulates AKR1D1 expression, regulation occurs through the mitogen-activated protein kinases/c-Jun Nterminal kinases (MAPK/JNK) signaling pathway | up |