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Literature summary for 1.3.1.24 extracted from

  • Whitby, F.G.; Phillips, J.D.; Hill, C.P.; McCoubrey, W.; Maines, M.D.
    Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex (2002), J. Mol. Biol., 319, 1199-1210.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
apo enzyme and in complex with NADH Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
Y97F 50% of activity compared to wild type Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P46844
-
-

Reaction

Reaction Comment Organism Reaction ID
bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+ catalysis via hydride transfer from NADH Rattus norvegicus

Subunits

Subunits Comment Organism
More general acid in catalysis is Y97 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADH
-
Rattus norvegicus