Inhibitors | Comment | Organism | Structure |
---|---|---|---|
17beta-estradiol | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Rattus norvegicus | |
0.00027 | - |
progesterone | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | nuclear and cell-debris fraction | Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
female rat | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hypophysis | anterior | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
20alpha-hydroxy-4-pregnen-3-one + NADPH | more reactive than progesterone | Rattus norvegicus | 20alpha-hydroxy-5-beta-pregnan-3-one + NADP+ | - |
? | |
additional information | testosterone and 20alpha-hydroxy-4-pregnen-3-one can act in place of progesterone | Rattus norvegicus | ? | - |
? | |
additional information | testosterone is less effective | Rattus norvegicus | ? | - |
? | |
progesterone + NADPH + H+ | - |
Rattus norvegicus | 5alpha-pregnan-3-20-dione + NADP+ | - |
? | |
testosterone + NADPH + H+ | very low activity | Rattus norvegicus | 5alpha-dihydrotestosterone + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | cannot be replaced by NADH | Rattus norvegicus |