Activating Compound | Comment | Organism | Structure |
---|---|---|---|
interleukin-6 | stimulates enzyme expression | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
chrysin | inhibits enzyme expression at concentrations higher than 0.01 mM; inhibits enzyme expression at concentrations higher than 0.01 mM | Homo sapiens | |
additional information | enzyme expression is not inhibited by baicalin and baicalein; enzyme expression is not inhibited by baicalin and baicalein | Homo sapiens | |
wogonin | inhibits enzyme expression at concentrations higher than 0.0025 mM; inhibits enzyme expression at concentrations higher than 0.0025 mM | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34000 | - |
SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P52895 | aldo-keto reductase family 1 member C2, AKR1C2 | - |
Homo sapiens | Q04828 | aldo-keto reductase family 1 member C1, AKR1C1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
non-small cell lung cancer cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
trans-1,2-dihydrobenzene-1,2-diol + NAD(P)+ | - |
Homo sapiens | catechol + NAD(P)H | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AKR1C1 | - |
Homo sapiens |
AKR1C2 | - |
Homo sapiens |
DDH | member of the aldo-keto reductases superfamily which plays a central role in the metabolism of steroid hormones, prostaglandins and xenobiotics | Homo sapiens |
dihydrodiol dehydrogenase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD(P)+ | - |
Homo sapiens |