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Literature summary for 1.3.1.20 extracted from

  • Wang, L.S.; Chow, K.C.; Wu, Y.C.; Lin, T.Y.; Li, W.Y.
    Inverse expression of dihydrodiol dehydrogenase and glutathione-S-transferase in patients with esophageal squamous cell carcinoma (2004), Int. J. Cancer, 111, 246-251.
    View publication on PubMed

Application

Application Comment Organism
medicine enzyme overexpression is detected in 66.9% of pathological sections and in 41.6% of metastatic lymph nodes in patients with esophageal squamous cell carcinoma, the major isoform is DDH2. Enzyme overexpression is positively correlated with smoking habit, tumor stage, number of metastatic lymph nodes, lymphovascular invasion and COX-2 expression, and inversely correlated with glutathione-S-transferase and nm23-HI expression. Patients with low enzyme expression have significantly lower incidence of tumor recurrences and better survival Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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patients with esophageal squamous cell carcinoma
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