Protein Variants | Comment | Organism |
---|---|---|
R235Q | the mutation is expected to weaken the binding of the FAD ring system and to change the electronic environment and hence, the redox potential of the cofactor | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
thymine + NADPH + H+ | - |
Homo sapiens | 5,6-dihydrothymine + NADP+ | - |
? | |
uracil + NADPH + H+ | - |
Homo sapiens | 5,6-dihydrouracil + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dihydropyrimidine dehydrogenase | - |
Homo sapiens |
DPD | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Homo sapiens |