Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-hydroxyphenylpyruvate | - |
Bacillus subtilis | |
D-tyrosine | - |
Bacillus subtilis | |
L-phenylalanine | - |
Bacillus subtilis | |
L-tryptophan | - |
Bacillus subtilis | |
L-tyrosine | - |
Bacillus subtilis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1 | - |
NAD+ | - |
Bacillus subtilis | |
2 | - |
prephenate | - |
Bacillus subtilis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
KCl | required for optimal activity | Bacillus subtilis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
prephenate + NAD+ | Bacillus subtilis | biosynthesis of L-tyrosine | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Bacillus subtilis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
prephenate + NAD+ | - |
Bacillus subtilis | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
prephenate + NAD+ | biosynthesis of L-tyrosine | Bacillus subtilis | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
32 | - |
- |
Bacillus subtilis |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
decrease of activity above | Bacillus subtilis |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
L-tyrosine, protection against thermal inactivation | Bacillus subtilis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.4 | - |
- |
Bacillus subtilis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | NADP+ cannot substitute for NAD+ | Bacillus subtilis | |
NAD+ | - |
Bacillus subtilis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.003 | - |
L-tyrosine | - |
Bacillus subtilis | |
0.3 | - |
L-phenylalanine | - |
Bacillus subtilis | |
0.4 | - |
4-hydroxyphenylpyruvate | - |
Bacillus subtilis | |
0.7 | - |
L-tryptophan | - |
Bacillus subtilis | |
1.3 | - |
D-tyrosine | - |
Bacillus subtilis |