Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.3.1.100 extracted from

  • Cheng, J.; Coyle, C.; Panaccione, D.; O'Connor, S.
    A role for old yellow enzyme in ergot alkaloid biosynthesis (2010), J. Am. Chem. Soc., 132, 1776-1777.
    View publication on PubMed
Search for more literature for 1.3.1.100

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Aspergillus fumigatus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0401
-
 NADPH pH and temperature not specified in the publication Aspergillus fumigatus
0.048
-
 chanoclavine-I aldehyde pH and temperature not specified in the publication Aspergillus fumigatus

Organism

Organism UniProt Comment Textmining
Aspergillus fumigatus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Aspergillus fumigatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chanoclavine-I aldehyde + NADPH + H+
-
 Aspergillus fumigatus dihydrochanoclavine-I aldehyde + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
EasA
-
 Aspergillus fumigatus
old yellow enzyme
-
 Aspergillus fumigatus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
38.5
-
 chanoclavine-I aldehyde pH and temperature not specified in the publication Aspergillus fumigatus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Aspergillus fumigatus