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Literature summary for 1.21.4.1 extracted from

  • Bouillaut, L.; Self, W.T.; Sonenshein, A.L.
    Proline-dependent regulation of Clostridium difficile Stickland metabolism (2013), J. Bacteriol., 195, 844-854.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Clostridioides difficile Q17ZY6 selenium-containing subunit PrdB
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Clostridioides difficile 630 Q17ZY6 selenium-containing subunit PrdB
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Synonyms

Synonyms Comment Organism
PrdB
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Clostridioides difficile

Expression

Organism Comment Expression
Clostridioides difficile presence of proline activates transcription of the prd operon encoding D-proline reductase. Protein PrdR activates transcription of the poline reductase-encoding genes in the presence of proline up

General Information

General Information Comment Organism
physiological function addition of L-proline to the medium increases the growth rate of the wild-type strain but has no effect on the doubling time or the growth behavior of a prdB gene disruption mutant. Mutants are viable and do not exhibit a severe growth defect compared to the wild-type Clostridioides difficile