Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CoASH | - |
Moorella thermoacetica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
CoA | acetyl-CoA/CoA exchange reaction | Moorella thermoacetica | |
1.5 | - |
acetyl-CoA | acetyl-CoA/CoA exchange reaction | Moorella thermoacetica | |
5 | - |
propionyl-CoA | - |
Moorella thermoacetica |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
2 * 50000 + 2 * 71000 + 2 * 78000, alpha2beta2gamma2, SDS-PAGE | Moorella thermoacetica |
71000 | - |
2 * 50000 + 2 * 71000 + 2 * 78000, alpha2beta2gamma2, SDS-PAGE | Moorella thermoacetica |
78000 | - |
2 * 50000 + 2 * 71000 + 2 * 78000, alpha2beta2gamma2, SDS-PAGE | Moorella thermoacetica |
410000 | - |
gel filtration | Moorella thermoacetica |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Moorella thermoacetica | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
CO + H2O + 2 oxidized ferredoxin = CO2 + 2 reduced ferredoxin + 2 H+ | enzyme also catalyzes acetyl-CoA/CoA and acetyl-CoA/CO exchange reaction, enzyme has both CO-dehydrogenase and acetyl-CoA synthase activity | Moorella thermoacetica |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-SCoA + CO | acetyl-CoA/CO exchange reaction, 14C experiments prove that the enzyme can cleave both the carbon-carbon and carbon-sulfur bonds of acetyl-CoA as well as to store methyl, CO, and CoA fragments at the active site | Moorella thermoacetica | acetyl-SCoA + CO | - |
r | |
acetyl-SCoA + CoASH | acetyl-CoA/CoA exchange reaction | Moorella thermoacetica | acetyl-SCoA + CoASH | - |
r | |
CO + H2O + methyl viologen | catalyzes the exchange reaction between coenzyme A and acetyl-CoA | Moorella thermoacetica | CO2 + reduced methyl viologen | - |
? | |
CO + H2O + methyl viologen | catalyzes the exchange reaction between propionyl-CoA and CoA at 7% of the exchange with acetyl-CoA | Moorella thermoacetica | CO2 + reduced methyl viologen | - |
? | |
propionyl-SCoA + CoASH | acetyl-CoA/CoA exchange reaction | Moorella thermoacetica | propionyl-SCoA + CoASH | - |
r |
Subunits | Comment | Organism |
---|---|---|
hexamer | 2 * 50000 + 2 * 71000 + 2 * 78000, alpha2beta2gamma2, SDS-PAGE | Moorella thermoacetica |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.007 | - |
CoASH | - |
Moorella thermoacetica |